PDB: 1xtc Compound: cholera toxin Classification: TOXIN Entry date in PDB: 1996-08-01 Resolution [Å]: 2.40 R-Factor: 0.185

CHAIN: A SWISS-PROT/TREMBL: P01555    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Glycosyltransferase    NAD    Signal    Transferase    EC: 2.4.2.36 SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Cholera toxin    Vibrio cholerae GO:  extracellular region    catalytic activity    pathogenesis    CHAIN: C SWISS-PROT/TREMBL: P01555    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Glycosyltransferase    NAD    Signal    Transferase    EC: 2.4.2.36 SCOP: d.166.1.1 Alpha and beta proteins (a+b)    ADP-ribosylation    ADP-ribosylation    ADP-ribosylating toxins    Cholera toxin    Vibrio cholerae GO:  extracellular region    catalytic activity    pathogenesis    CHAIN: D SWISS-PROT/TREMBL: P01556    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Membrane    Signal    SCOP: b.40.2.1 All beta proteins    OB-fold    Bacterial enterotoxins    Bacterial AB5 toxins, B-subunits    Cholera toxin    Vibrio cholerae GO:  extracellular region    pathogenesis    CHAIN: E SWISS-PROT/TREMBL: P01556    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Membrane    Signal    SCOP: b.40.2.1 All beta proteins    OB-fold    Bacterial enterotoxins    Bacterial AB5 toxins, B-subunits    Cholera toxin    Vibrio cholerae GO:  extracellular region    pathogenesis    CHAIN: F SWISS-PROT/TREMBL: P01556    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Membrane    Signal    SCOP: b.40.2.1 All beta proteins    OB-fold    Bacterial enterotoxins    Bacterial AB5 toxins, B-subunits    Cholera toxin    Vibrio cholerae GO:  extracellular region    pathogenesis    CHAIN: G SWISS-PROT/TREMBL: P01556    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Membrane    Signal    SCOP: b.40.2.1 All beta proteins    OB-fold    Bacterial enterotoxins    Bacterial AB5 toxins, B-subunits    Cholera toxin    Vibrio cholerae GO:  extracellular region    pathogenesis    CHAIN: H SWISS-PROT/TREMBL: P01556    KEYWORD: 3D-structure    Complete proteome    Enterotoxin    Membrane    Signal    SCOP: b.40.2.1 All beta proteins    OB-fold    Bacterial enterotoxins    Bacterial AB5 toxins, B-subunits    Cholera toxin    Vibrio cholerae GO:  extracellular region    pathogenesis

Image Source: PDB

Loops in ArchDB-EC clusters

1xtc_A_124 - HA => SUBCLASS : 2.1.1

Loops not clustered in ArchDB

1xtc_A_112 - AR
1xtc_A_83 - AR
1xtc_A_6 - EH
1xtc_A_21 - EH
1xtc_A_59 - EH
1xtc_A_94 - EH
1xtc_A_135 - EH
1xtc_A_119 - HA
1xtc_A_67 - HE
1xtc_A_97 - HE
1xtc_A_13 - HE
1xtc_A_41 - HE

1djr D - percentage of sequence identity: 80
1htl A - percentage of sequence identity: 85
1lt3 A - percentage of sequence identity: 84
1lt4 A - percentage of sequence identity: 85
1lta A - percentage of sequence identity: 86
1ltb A - percentage of sequence identity: 87
1ltg A - percentage of sequence identity: 85
1lti A - percentage of sequence identity: 85
1ltt A - percentage of sequence identity: 87
1s5b A - percentage of sequence identity: 98
1s5c A - percentage of sequence identity: 98
1s5d A - percentage of sequence identity: 100
1s5e A - percentage of sequence identity: 98
1s5e B - percentage of sequence identity: 98
1s5f A - percentage of sequence identity: 98
2a5d B - percentage of sequence identity: 97
2a5f B - percentage of sequence identity: 97
2a5g B - percentage of sequence identity: 97
3chb D - percentage of sequence identity: 95