PDB: 2uag Compound: udp-n-acetylmuramoyl-l-alanine Classification: LIGASE Entry date in PDB: 2000-02-25 Resolution [Å]: 1.70 R-Factor: 0.180

CHAIN: A SWISS-PROT/TREMBL: P14900    KEYWORD: 3D-structure    ATP-binding    Cell division    Cell wall    Complete proteome    Ligase    Peptidoglycan synthesis    EC: 6.3.2.9 SCOP: c.5.1.1 Alpha and beta proteins (a/b)    MurCD N-terminal domain    MurCD N-terminal domain    MurCD N-terminal domain    UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD    Escherichia coli SCOP: c.59.1.1 Alpha and beta proteins (a/b)    MurD-like peptide ligases, peptide-binding domain    MurD-like peptide ligases, peptide-binding domain    MurCDEF C-terminal domain    UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD    Escherichia coli SCOP: c.72.2.1 Alpha and beta proteins (a/b)    Ribokinase-like    MurD-like peptide ligases, catalytic domain    MurCDEF    UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD    Escherichia coli GO:  cytoplasm    ATP binding    ligase activity    UDP-N-acetylmuramoylalanine-D-glutamate ligase activity    biosynthesis    cell wall biosynthesis (sensu Bacteria)

Image Source: PDB

Loops in ArchDB40 clusters

2uag_A_247 - HA => SUBCLASS : 2.1.1
2uag_A_304 - HA => SUBCLASS : 2.1.3
2uag_A_90 - EH => SUBCLASS : 1.1.1
2uag_A_90 - EH => SUBCLASS : 1.1.2
2uag_A_153 - EH => SUBCLASS : 1.1.6
2uag_A_153 - EH => SUBCLASS : 1.1.12
2uag_A_364 - EH => SUBCLASS : 1.2.19
2uag_A_384 - EH => SUBCLASS : 2.1.2
2uag_A_384 - EH => SUBCLASS : 2.1.6
2uag_A_8 - EH => SUBCLASS : 3.2.1
2uag_A_312 - EH => SUBCLASS : 6.23.1
2uag_A_266 - HH => SUBCLASS : 3.3.1

Loops in ArchDB95 clusters

2uag_A_90 - EH => SUBCLASS : 1.1.1
2uag_A_153 - EH => SUBCLASS : 1.1.6
2uag_A_364 - EH => SUBCLASS : 1.3.4
2uag_A_384 - EH => SUBCLASS : 2.1.3
2uag_A_153 - EH => SUBCLASS : 2.2.1
2uag_A_8 - EH => SUBCLASS : 3.5.1
2uag_A_312 - EH => SUBCLASS : 6.14.1
2uag_A_266 - HH => SUBCLASS : 3.2.1
2uag_A_79 - HE => SUBCLASS : 1.2.1
2uag_A_115 - HE => SUBCLASS : 2.1.1
2uag_A_59 - HE => SUBCLASS : 2.2.3
2uag_A_79 - HE => SUBCLASS : 2.5.1
2uag_A_15 - HE => SUBCLASS : 3.5.1
2uag_A_94 - HE => SUBCLASS : 4.15.2
2uag_A_15 - HE => SUBCLASS : 4.53.1
2uag_A_390 - HE => SUBCLASS : 5.8.3
2uag_A_304 - HA => SUBCLASS : 2.1.5
2uag_A_304 - HA => SUBCLASS : 2.1.6

Loops not clustered in ArchDB

2uag_A_106 - EH
2uag_A_406 - EH
2uag_A_253 - EH
2uag_A_173 - EH
2uag_A_67 - EH
2uag_A_52 - EH
2uag_A_32 - HA
2uag_A_339 - HA
2uag_A_237 - HA
2uag_A_227 - HA
2uag_A_207 - HA
2uag_A_133 - HA
2uag_A_323 - HE
2uag_A_286 - HE
2uag_A_190 - HE
2uag_A_160 - HE
2uag_A_373 - HE

1e0d A - percentage of sequence identity: 100
1eeh A - percentage of sequence identity: 100
1uag - - percentage of sequence identity: 100
3uag A - percentage of sequence identity: 100