PDB: 4cd2 Compound: dihydrofolate reductase Classification: OXIDOREDUCTASE Entry date in PDB: 2000-03-29 Resolution [Å]: 2.00 R-Factor: 0.176

CHAIN: A SWISS-PROT/TREMBL: P16184    KEYWORD: 3D-structure    NADP    One-carbon metabolism    Oxidoreductase    EC: 1.5.1.3 SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases, eukaryotic type    Fungus (Pneumocystis carinii) GO:  dihydrofolate reductase activity    glycine biosynthesis    nucleotide biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

4cd2_A_126 - HE => SUBCLASS : 3.3.4
4cd2_A_190 - HA => SUBCLASS : 2.4.2
4cd2_A_7 - HA => SUBCLASS : 3.1.2
4cd2_A_93 - EH => SUBCLASS : 0.1.1
4cd2_A_169 - EH => SUBCLASS : 1.1.4
4cd2_A_169 - EH => SUBCLASS : 1.1.12
4cd2_A_93 - EH => SUBCLASS : 2.1.1
4cd2_A_115 - EH => SUBCLASS : 3.27.1

Loops in ArchDB95 clusters

4cd2_A_93 - EH => SUBCLASS : 2.1.1
4cd2_A_169 - EH => SUBCLASS : 2.2.1
4cd2_A_115 - EH => SUBCLASS : 3.40.1
4cd2_A_190 - HA => SUBCLASS : 2.1.4
4cd2_A_190 - HA => SUBCLASS : 2.5.1

Loops not clustered in ArchDB

4cd2_A_138 - AR
4cd2_A_152 - AR
4cd2_A_18 - EH
4cd2_A_50 - EH
4cd2_A_76 - HA
4cd2_A_30 - HE
4cd2_A_59 - HE
4cd2_A_98 - HE
4cd2_A_174 - HE

1cd2 A - percentage of sequence identity: 100
1daj - - percentage of sequence identity: 100
1e26 A - percentage of sequence identity: 100
1klk A - percentage of sequence identity: 100
1ly3 A - percentage of sequence identity: 100
1ly4 A - percentage of sequence identity: 100
1s3y A - percentage of sequence identity: 100
1vj3 A - percentage of sequence identity: 100
2cd2 A - percentage of sequence identity: 100
3cd2 A - percentage of sequence identity: 100