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Information on SUBCLASS 10.2.1
Subclass Accession number: 2542
Subclass: 10.2.1 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.7.1 (>75 %)  2.7.1.37
GO : GO:0003700 (>75 %)  GO:0003707 (>75 %)  GO:0004672 (>50 %)  GO:0004872 (>75 %)  GO:0004879 (>75 %)  GO:0005549 (>75 %)  GO:0016301 (>50 %)  GO:0016773 (>50 %)  
SCOP : 47472 (>75 %)  47565 (>75 %)  47566 (>75 %)  48507 (>75 %)  48508 (>75 %)  48509 (>75 %)  56111 (>75 %)  56112 (>75 %)  88854 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 17.2 +/- 14.5
Average RMSD (Å) : 0.933 +/- 0.115

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 45-90 rho (°): 315-360
Consensus Sequence: XhXXhcXphphpXX
(φψ)-conformation: aalabpaalpppaa
Pattern: [PQR][DES][ILT][GMT][C][AY][IMT][KMY][C][LV]xx[AKM][AFL][GNS][LMT][LV][DN][DKP][EK][AG][EN][FLV][DHN]x[DGP]x[AM][LM][AEG]x
Conservation:-0.376-0.048-0.376-0.8683.3400.172-0.431-0.5953.3400.208-0.457-0.868-0.649-0.649-0.103-0.3210.2120.744-0.4310.4760.4080.459-0.3210.116-0.485-0.485-0.923-0.1750.494-0.595-0.813
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1dqe_A_461dqe   A4676RETGCAIMCLSTKLNMLDPEGNLHHGNAMEFHHHHHHHHHHHHHTT-B-TTSSB-HHHHHHHaaaaaaaaaaaaaalabxaavxxxaaaaaaa
1ooh_A_421ooh   A4272QDLMCYTKCVSLMAGTVNKKGEFNAPKALAQHHHHHHHHHHHHHHTSB-TT--B-HHHHHHHaaaaaaaaaaaaaavabxaavxxbaaaaaaa
1r5r_A_431r5r   A4373PSITCYMYCLLEAFSLVDDEANVDEDIMLGLHHHHHHHHHHHHHTTSB-TT--B-HHHHHHHaaaaaaaaaaaaaalabbaalxxxaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL I - 52
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL M - 53
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL S - 56
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL M - 61
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL L - 62
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL G - 66
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL L - 68
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL A - 73
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL F - 76
1dqe_A_461dqe   A     BOMHEXADECA-10,12-DIEN-1-OL A - 77
1ooh_A_421ooh   A     1BO1-BUTANOL T - 48
1ooh_A_421ooh   A     1BO1-BUTANOL V - 51
1ooh_A_421ooh   A     1BO1-BUTANOL S - 52
1ooh_A_421ooh   A     1BO1-BUTANOL A - 55
1ooh_A_421ooh   A     1BO1-BUTANOL G - 56
1ooh_A_421ooh   A     1BO1-BUTANOL T - 57
1ooh_A_421ooh   A     1BO1-BUTANOL V - 58
1ooh_A_421ooh   A     1BO1-BUTANOL F - 64
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE Y - 48
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE M - 49
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE Y - 50
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE L - 52
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE L - 53
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE F - 56
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE L - 58
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE M - 70
1r5r_A_431r5r   A     NBBN-BUTYL-BENZENESULFONAMIDE L - 73

Clusters included in this Subclass
CLUSTER: HH.10.12