ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.12.2

Subclass Accession number: 4813
Subclass: 4.12.2

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
SCOP : 47026 (>75 %)

Number of loops: 5

Average sequence ID (%) : 20.8 +/- 21.6
Average RMSD (Å) : 0.520 +/- 0.164

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	pXpcXXpE
(φψ)-conformation:	aapgppaa

Pattern:	[fkw]	[DEG]	[EKQR]	[AKRS]	[IKL]	[QRTWY]	[ADEKN]	[aw]	[HVWY]	[AEKNS]	[es]	[HLV]	[EKR]	[DGN]	x	[anps]	[kr]	[DE]	[DEK]	[ASV]	[EMQ]	[KM]	[AER]	[IY]	[IKLV]
Conservation:	-0.937	0.494	0.632	-0.315	-0.852	-1.054	-0.695	-0.772	0.168	-0.615	-0.652	-0.770	1.045	0.688	-0.671	-1.533	-0.166	2.484	1.191	0.210	0.012	0.745	-0.409	2.250	-0.477

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1h4r_A_181	1h4r	A	184	208	WEERITAWYAEHRGRARDEAEMEYL	HHHHHHHHHHTTTT--HHHHHHHHH	aaaaaaaaaaaapvxxaaaaaaaaa
1hb6_A_49	1hb6	A	50	74	KGKAKWDAWNELKGTSKEDAMKAYI	HHHHHHHHHHHTTT--HHHHHHHHH	aaaaaaaaaaaapgxxaaaaaaaaa
1hbk_A_51	1hbk	A	52	76	IDRKKYEAWKSVENLNREDAQKRYV	HHHHHHHHHHHTTT--HHHHHHHHH	aaaaaaaaaaaapvxxaaaaaaaaa
1j19_A_165	1j19	A	168	192	WEERIQNWHEEHRGMLREDSMMEYL	HHHHHHHHHHTTTT--HHHHHHHHH	aaaaaaaaaaaapgxxaaaaaaaaa
1j97_A_49	1j97	A	49	73	FEQSLRKRVSLLKDLPIEKVEKAIK	HHHHHHHHHHTTTT-BHHHHHHHHH	aaaaaaaaaaaapvxxaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1hbk_A_51	1hbk	A	COACOENZYME A	I - 52
1hbk_A_51	1hbk	A	MYRMYRISTIC ACID	I - 52
1hbk_A_51	1hbk	A	COACOENZYME A	D - 53
1hbk_A_51	1hbk	A	COACOENZYME A	K - 56
1hbk_A_51	1hbk	A	MYRMYRISTIC ACID	K - 56
1hbk_A_51	1hbk	A	COACOENZYME A	W - 60
1hbk_A_51	1hbk	A	COACOENZYME A	Y - 75
1hbk_A_51	1hbk	A	MYRMYRISTIC ACID	Y - 75
1j97_A_49	1j97	A	BFDASPARTATE BERYLLIUM TRIFLUORIDE	F - 49

Clusters included in this Subclass