ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.6.1

Subclass Accession number: 6002
Subclass: 10.6.1

Type: HE alpha-beta
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7 (>75 %)  2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.37 2.7.3 (>75 %)  2.7.3.2
GO : GO:0004111 (>75 %)  GO:0004672 (>75 %)  GO:0004702 (>50 %)  GO:0004707 (>50 %)  GO:0005057 (>50 %)  GO:0005515 (>50 %)  GO:0016301 (>75 %)  GO:0016301 (>75 %)  GO:0016772 (>75 %)  GO:0016772 (>75 %)  GO:0016773 (>75 %)  GO:0016775 (>75 %)
SCOP : 55930 (>75 %)  55931 (>75 %)  55935 (>75 %)  56111 (>75 %)  56112 (>75 %)  88854 (>75 %)

Number of loops: 3

Average sequence ID (%) : 44.8 +/- 18.8
Average RMSD (Å) : 1.000 +/- 0.361

Consensus geometry

d (Å): 11

delta (°): 90-135

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	KphpHXNVhXLLch
(φψ)-conformation:	aapbbaabpbpabb

Pattern:	x	[GIL]	[EFH]	[AV]	[KS]	[QR]	[AFT]	[LY]	[RT]	[E]	[GL]	x	[IL]	[LM]	[K]	[DH]	[FM]	[KRS]	[H]	[EP]	[N]	[V]	[IL]	[GS]	[L]	[L]	[DG]	[IV]	[CF]
Conservation:	-1.147	-1.542	-0.956	-0.492	-0.320	0.095	-1.217	-0.268	-0.488	1.260	-1.410	-1.194	0.091	0.215	1.260	0.151	-0.073	-0.630	3.020	-0.240	1.847	0.674	0.091	-0.149	0.674	0.674	-0.193	0.382	-0.113

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1cm8_A_65	1cm8	A	65	93	ELFAKRAYRELRLLKHMRHENVIGLLDVF	HHHHHHHHHHHHHHHH--BTTB---SEEE	aaaaaaaaaaaaaaaaxbbaabpbxabbb
1r0p_A_1118	1r0p	A	1118	1146	IGEVSQFLTEGIIMKDFSHPNVLSLLGIC	HHHHHHHHHHHHHHHT---TTB----EEE	aaaaaaaaaaaaaaaaxxbaabxxxaebb
1r3c_A_62	1r3c	A	62	90	IIHAKRTYRELRLLKHMKHENVIGLLDVF	HHHHHHHHHHHHHHHH---TTB---SEEE	aaaaaaaaaaaaaaaaxbbaabxbxabbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1cm8_A_65	1cm8	A	TPOPHOSPHOTHREONINE	L - 66
1cm8_A_65	1cm8	A	TPOPHOSPHOTHREONINE	K - 69
1cm8_A_65	1cm8	A	TPOPHOSPHOTHREONINE	R - 70
1cm8_A_65	1cm8	A	PTRO-PHOSPHOTYROSINE	R - 70
1cm8_A_65	1cm8	A	TPOPHOSPHOTHREONINE	R - 73
1cm8_A_65	1cm8	A	MGMAGNESIUM ION	E - 74
1cm8_A_65	1cm8	A	ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	E - 74
1cm8_A_65	1cm8	A	ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	I - 87
1r0p_A_1118	1r0p	A	KSAK-252A	L - 1140
1r3c_A_62	1r3c	A	MGMAGNESIUM ION	E - 81

Clusters included in this Subclass