ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 8.6.1

Subclass Accession number: 2527
Subclass: 8.6.1

Type: HH alpha-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.4 (>75 %)  2.4.1 (>75 %)  2.4.1.1 (>75 %)
GO : GO:0005083 (>75 %)  GO:0005085 (>75 %)  GO:0005509 (>75 %)  GO:0005515 (>75 %)  GO:0008603 (>75 %)  GO:0016208 (>75 %)  GO:0019207 (>75 %)  GO:0019887 (>75 %)  GO:0030551 (>75 %)  GO:0030552 (>75 %)  GO:0030695 (>75 %)
SCOP : 47472 (>75 %)  47473 (>75 %)  47492 (>75 %)  51181 (>75 %)  51206 (>75 %)  51210 (>75 %)  53755 (>75 %)  53756 (>75 %)  53766 (>75 %)

Number of loops: 4

Average sequence ID (%) : 10.5 +/- 13.1
Average RMSD (Å) : 0.900 +/- 0.283

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 90-135

rho (°): 270-315

Consensus Sequence:	XXXXXXpchXXc
(φψ)-conformation:	aapaaaaabpaa

Pattern:	x	[ACLV]	[DEH]	x	[AI]	[FHY]	x	x	[KL]	[AKLT]	x	x	[EKP]	[AKN]	[FLTY]	[EHKS]	[HKN]	[AFLY]	x	x	[GKNT]	x	[KLV]	x	x	x	[ACGM]
Conservation:	-0.482	0.146	1.747	-0.698	1.213	3.139	-0.554	-1.603	0.852	-0.624	-1.253	-0.344	0.979	-0.026	0.076	0.356	1.182	0.006	-0.694	-1.044	-0.204	-0.339	-0.087	-0.380	-0.764	-0.116	-0.484

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ax4_A_227	1ax4	A	227	253	FCENAYFIKARDPKYKNATIKEVIFDM	HHHHHHHHHHH-GGGTT--HHHHHHHH	aaaaaaaaaaabaaaaaxxaaaaaaaa
1kq3_A_250	1kq3	A	250	276	AAHAIHNGLTVLENTHKYLHGEKVAIG	HHHHHHHHHTTSGGGTTS-HHHHHHHH	aaaaaaaaaaabaaaaaxxaaaaaaaa
1o7f_A_28	1o7f	A	30	56	DVDIIFTRLKGVKAFEKFHPNLLRQIC	HHHHHHHHHTT-TTTTT--HHHHHHHH	aaaaaaaaaaaxaaaaabxaaaaaaaa
1o7f_A_323	1o7f	A	325	351	DLEIIYDELLHIKALSHLSTTVKRELA	HHHHHHHHHTT-GGGTTS-HHHHHHHH	aaaaaaaaaaaxaaaaabpaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1kq3_A_250	1kq3	A	ZNZINC ION	H - 252
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	H - 252
1kq3_A_250	1kq3	A	ZNZINC ION	H - 269
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	H - 269
1kq3_A_250	1kq3	A	ZNZINC ION	V - 273
1kq3_A_250	1kq3	A	TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	V - 273

Clusters included in this Subclass