ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 16.5.1

Subclass Accession number: 4321
Subclass: 16.5.1

Type: AR beta-beta link
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : - (>50 %)  21 (>50 %)  3 (>50 %)  4 (>50 %)
GO : GO:0004175 (>75 %)  GO:0004252 (>75 %)  GO:0008233 (>75 %)  GO:0008236 (>75 %)
SCOP : 50493 (>75 %)  50494 (>75 %)  50514 (>75 %)

Number of loops: 3

Average sequence ID (%) : 47.2 +/- 8.0
Average RMSD (Å) : 0.433 +/- 0.115

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 45-90

rho (°): 315-360

Consensus Sequence:	ChGpXppXpXXhXGDSGGPX
(φψ)-conformation:	bbepaababbpbpgapgppb

Pattern:	[MQ]	[FIV]	[C]	[AV]	[G]	[DSY]	[DP]	[ST]	[KT]	x	[EKR]	[ADN]	[AS]	[CF]	x	[G]	[D]	[S]	[G]	[G]	[P]	[HL]	[LV]	[CT]
Conservation:	-0.403	-0.668	2.465	-0.625	1.122	-1.215	-0.227	-0.238	-0.603	-1.166	-0.519	-1.066	-0.408	-0.383	-0.967	1.122	1.122	0.227	1.122	1.122	1.570	-0.990	-0.412	0.018

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1euf_A_180	1euf	A	180	203	QICAGDPSKRKNSFSGDSGGPLVC	EEEES-TTS--B--TT-TT-EEEE	bbbbexaababbxbpvapgxxxbb
1fjs_A_180	1fjs	A	180	203	MFCAGYDTKQEDACQGDSGGPHVT	EEEES-SSSS-B--TT-TT-EEEE	bbbbebaapabbxbpgapvxxbbb
3rp2_A_180	3rp2	A	180	203	QVCVGSPTTLRAAFMGDSGGPLLC	EEEE--TTS--B--TTTTT-EEEE	bbxbexaabaxbxbxgapvxxbxb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1fjs_A_180	1fjs	A	Z34N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE	M - 180
1fjs_A_180	1fjs	A	GOLGLYCEROL	M - 180
1fjs_A_180	1fjs	A	GOLGLYCEROL	F - 181
1fjs_A_180	1fjs	A	GOLGLYCEROL	C - 182

Clusters included in this Subclass

CLUSTER: AR.15.9