ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.50.1

Subclass Accession number: 4993
Subclass: 6.50.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0005506 (>75 %) GO:0046914 (>75 %)
SCOP : 47239 (>75 %) 47240 (>75 %) 47241 (>75 %)

Number of loops: 3

Average sequence ID (%) : 67.7 +/- -20.0
Average RMSD (Å) : 0.200 +/- 0.000

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	FcRDDhALpN
(φψ)-conformation:	aapaaalbaa

Pattern:	[QR]	[D]	[CS]	[E]	[A]	[AG]	[IL]	[N]	[R]	x	[IV]	[N]	[LM]	[EK]	[FL]	[HY]	[AS]	[S]	[Y]	[TV]	[Y]	[L]	[S]	[M]	[AS]	x	[Y]	[F]	[DN]	[R]	[D]	[D]	[IV]	[A]	[L]	[HKS]	[N]	[FV]	[A]	[K]	[FY]	[F]	x	[EH]	[QR]	[S]	[EH]	[E]	[E]	[KR]	[E]	[H]	[A]	[E]	[K]	[L]	[IM]	[EK]	x	[Q]	[N]	[KQ]	[R]
Conservation:	-0.677	1.162	-0.555	0.539	-0.083	-1.069	-0.698	1.162	0.539	-1.813	-0.387	1.162	-0.580	-0.689	-1.069	0.370	-1.005	-0.083	1.784	-1.188	1.784	-0.083	-0.083	0.539	-0.994	-1.536	1.784	1.162	-0.374	0.539	1.162	1.162	-0.387	-0.083	-0.083	-1.675	1.162	-1.190	-0.083	0.539	0.362	1.162	-1.882	-0.648	-0.689	-0.083	-0.415	0.539	0.539	-0.382	0.539	2.407	-0.083	0.539	0.539	-0.083	-0.811	-0.689	-2.505	0.539	1.162	-0.677	0.539

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bg7_*_10	1bg7	-	10	72	RDCEAAINRMVNMELYASYTYLSMAFYFDRDDIALHNVAKFFKEQSHEEREHAEKLMKDQ	HHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTT--HHHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaaaapaaalbaaaaaaaaaaaaaaaaaaaaaaaaa
1rcd_*_10	1rcd	-	10	72	QDCEAGLNRTVNLKFHSSYVYLSMASYFNRDDVALSNFAKFFRERSEEEKEHAEKLIEYQ	HHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTT--HHHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaaaaxaaalbaaaaaaaaaaaaaaaaaaaaaaaaa
2fha_*_14	2fha	-	14	76	QDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQ	HHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTT--HHHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaaaaaaaaaaaaaxaaalbaaaaaaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
2fha_*_14	2fha	*	FOXTHESE RESIDUES FORM THE CATALYTIC FERROXIDASE CENTER WHICH CATALYZES THE CONVERSION OF FE2+ TO FE3+ AS THE FIRST STAGE OF IRON STORAGE IN THE FERRITINS.	E - 27
2fha_*_14	2fha	*	FOXTHESE RESIDUES FORM THE CATALYTIC FERROXIDASE CENTER WHICH CATALYZES THE CONVERSION OF FE2+ TO FE3+ AS THE FIRST STAGE OF IRON STORAGE IN THE FERRITINS.	Y - 34
2fha_*_14	2fha	*	FOXTHESE RESIDUES FORM THE CATALYTIC FERROXIDASE CENTER WHICH CATALYZES THE CONVERSION OF FE2+ TO FE3+ AS THE FIRST STAGE OF IRON STORAGE IN THE FERRITINS.	E - 61
2fha_*_14	2fha	*	FOXTHESE RESIDUES FORM THE CATALYTIC FERROXIDASE CENTER WHICH CATALYZES THE CONVERSION OF FE2+ TO FE3+ AS THE FIRST STAGE OF IRON STORAGE IN THE FERRITINS.	E - 62
2fha_*_14	2fha	*	FOXTHESE RESIDUES FORM THE CATALYTIC FERROXIDASE CENTER WHICH CATALYZES THE CONVERSION OF FE2+ TO FE3+ AS THE FIRST STAGE OF IRON STORAGE IN THE FERRITINS.	H - 65

Clusters included in this Subclass