ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 9.11.1

Subclass Accession number: 5079
Subclass: 9.11.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 2.7.3 (>75 %)  2.7.3.2 3.2 (>75 %)  3.2.1 (>75 %)  3.2.1.21
GO : GO:0004111 (>75 %)  GO:0004553 (>75 %)  GO:0015926 (>75 %)  GO:0016301 (>75 %)  GO:0016775 (>75 %)  GO:0016798 (>75 %)
SCOP : 51350 (>75 %)  51445 (>75 %)  51521 (>75 %)  55930 (>75 %)  55931 (>75 %)  55935 (>75 %)

Number of loops: 4

Average sequence ID (%) : 52.3 +/- 18.9
Average RMSD (Å) : 0.250 +/- 0.058

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hXGVHAPGhpchp
(φψ)-conformation:	aalabpwlpbbaa

Pattern:	[P]	[W]	[CV]	x	[A]	[FI]	[LV]	[GS]	[HNY]	[GLMW]	x	[G]	x	[H]	[A]	[P]	[G]	x	[RT]	[DN]	[ILP]	x	[ATV]	[A]	[FIL]	[DR]	[AV]	[AGV]	[H]	[HN]	[L]	x	x	[AG]	[H]	[AG]	x	[AS]	[V]	[EKQR]	x	[FL]	[R]	[ADE]
Conservation:	1.512	3.132	0.161	-0.936	0.297	-0.135	-0.269	-0.116	-0.120	-1.172	-1.172	1.107	-0.738	1.917	0.297	1.512	1.107	-0.764	-0.513	0.095	-0.963	-1.096	-0.738	0.297	-0.508	-0.551	-0.449	-0.926	1.917	0.487	0.297	-0.884	-1.060	-0.343	1.917	-0.135	-0.780	-0.263	0.297	-0.463	-1.060	-0.256	0.702	-0.637

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1e4i_A_167	1e4i	A	167	210	PWCIAFLSNMLGVHAPGLTNLQTAIDVGHHLLVAHGLSVRRFRE	HHHHHHHHHTS--STT----HHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaavabpwvxbbaaaaaaaaaaaaaaaaaaaaaaaa
1gnx_A_179	1gnx	A	179	222	PWCSAFLGYGSGVHAPGRTDPVAALRAAHHLNLGHGLAVQALRD	HHHHHHHHHTS-SSTT----HHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaavabpwvxbbaaaaaaaaaaaaaaaaaaaaaaaa
1oim_A_167	1oim	A	167	210	PWVVAIVGHLYGVHAPGMRDIYVAFRAVHNLLRAHARAVKVFRE	HHHHHHHHHTS-SSTT----HHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaavabpwvbbbaaaaaaaaaaaaaaaaaaaaaaaa
1ug6_A_165	1ug6	A	165	208	PWCSAFLGHWTGEHAPGLRNLEAALRAAHHLLLGHGLAVEALRA	HHHHHHHHHTS-SSTT----HHHHHHHHHHHHHHHHHHHHHHHH	aaaaaaaaaaavabpwvxbbaaaaaaaaaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1e4i_A_167	1e4i	A	NFG2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-ALLOPYRANOSIDE	V - 199
1e4i_A_167	1e4i	A	NFG2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-ALLOPYRANOSIDE	L - 203
1e4i_A_167	1e4i	A	NFG2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-ALLOPYRANOSIDE	R - 207
1gnx_A_179	1gnx	A	SUCSUCROSE	Q - 218
1ug6_A_165	1ug6	A	GOLGLYCEROL	C - 167
1ug6_A_165	1ug6	A	GOLGLYCEROL	L - 171
1ug6_A_165	1ug6	A	GOLGLYCEROL	G - 176
1ug6_A_165	1ug6	A	GOLGLYCEROL	H - 178
1ug6_A_165	1ug6	A	GOLGLYCEROL	G - 181
1ug6_A_165	1ug6	A	GOLGLYCEROL	L - 182
1ug6_A_165	1ug6	A	GOLGLYCEROL	R - 183
1ug6_A_165	1ug6	A	GOLGLYCEROL	N - 184
1ug6_A_165	1ug6	A	GOLGLYCEROL	E - 186
1ug6_A_165	1ug6	A	GOLGLYCEROL	A - 187

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gnx_A_179	1gnx	A	AC2SO4 BINDING SITE FOR CHAIN A	R - 204
1gnx_A_179	1gnx	A	AC1SUC BINDING SITE FOR CHAIN A	Q - 218

Clusters included in this Subclass