ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.22.1

Subclass Accession number: 678
Subclass: 4.22.1

Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1 (>75 %)  3 (>75 %)  3.4 (>75 %)  4 (>75 %)
GO : GO:0000107 (>75 %)  GO:0008233 (>75 %)  GO:0016757 (>75 %)  GO:0016763 (>75 %)  GO:0016829 (>75 %)
SCOP : 51350 (>75 %)  51366 (>75 %)  51367 (>75 %)

Number of loops: 4

Average sequence ID (%) : 8.3 +/- 12.7
Average RMSD (Å) : 1.100 +/- 0.216

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	hXXhXhph
(φψ)-conformation:	bbaaapbb

Pattern:	[AFY]	x	x	x	x	[AMPV]	x	[FLVW]
Conservation:	0.895	-1.582	0.877	1.038	0.005	-0.624	-1.103	0.495

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1h6l_A_221	1h6l	A	225	232	AEEDEAIW	EETTTEEE	xxaaabbb
1jyr_A_118	1jyr	A	118	125	YFLWVVKF	EESSS-EE	bbaaaxbb
1nzo_A_221	1nzo	A	228	235	ATEGQMRL	EESSS-EE	bbaaaxbb
2apr_*_307	2apr	-	311	318	FNQGVPEV	EETTTTEE	xbaaawbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1h6l_A_221	1h6l	A	CACALCIUM ION	E - 227
1h6l_A_221	1h6l	A	PO4PHOSPHATE ION	E - 227

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h6l_A_221	1h6l	A	AC5ACTIVITY CA 405 BINDING SITE FOR CHAIN A	E - 227

Clusters included in this Subclass

CLUSTER: HA.3.110