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Information on 1a8r
PDB: 1a8r
Compound: gtp cyclohydrolase i
Classification: HYDROLASE
Entry date in PDB: 1999-05-11
Resolution [Å]: 2.10
R-Factor: 0.200


CHAIN: A
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: B
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: C
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: D
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: E
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: F
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: G
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: H
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: I
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: J
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: K
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: L
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: M
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: N
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   


CHAIN: O
SWISS-PROT/TREMBL: P27511
   KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Hydrolase    One-carbon metabolism   
EC: 3.5.4.16
SCOP: d.96.1.1 Alpha and beta proteins (a+b)    T-fold    Tetrahydrobiopterin biosynthesis enzymes-like    GTP cyclohydrolase I    GTP cyclohydrolase I    Escherichia coli
GO:  GTP cyclohydrolase I activity    biosynthesis   
1a8r Image
Image Source: PDB

Stored Loops of 1a8r

Loops in ArchDB40 clusters

1a8r_A_171 - EH => SUBCLASS : 0.1.19
1a8r_A_148 - EH => SUBCLASS : 0.1.30
1a8r_A_148 - EH => SUBCLASS : 1.1.1
1a8r_A_171 - EH => SUBCLASS : 1.1.1
1a8r_A_130 - EH => SUBCLASS : 1.1.1
1a8r_A_148 - EH => SUBCLASS : 1.1.2
1a8r_A_194 - EH => SUBCLASS : 1.2.7
1a8r_A_194 - EH => SUBCLASS : 1.5.1
1a8r_A_202 - HH => SUBCLASS : 1.2.8

Loops in ArchDB95 clusters

1a8r_A_171 - EH => SUBCLASS : 0.1.3
1a8r_A_148 - EH => SUBCLASS : 1.1.1
1a8r_A_130 - EH => SUBCLASS : 1.1.13
1a8r_A_194 - EH => SUBCLASS : 1.3.3
1a8r_A_115 - AR => SUBCLASS : 3.10.4
1a8r_A_202 - HH => SUBCLASS : 1.1.21
1a8r_A_202 - HH => SUBCLASS : 1.2.11

Loops in ArchDB-EC clusters

1a8r_A_202 - HH => SUBCLASS : 1.2.5

Loops not clustered in ArchDB

1a8r_A_115 - AR
1a8r_A_88 - AR
1a8r_A_88 - AR
1a8r_A_99 - HA
1a8r_A_99 - HA
1a8r_A_62 - HE
1a8r_A_180 - HE
1a8r_A_151 - HE
1a8r_A_134 - HE
1a8r_A_32 - HH
1a8r_A_5 - HH
1a8r_A_57 - HH

Homologous structures to 1a8r classified in ArchDB

1a8r A - percentage of sequence identity: 100
1a8r B - percentage of sequence identity: 100
1a8r C - percentage of sequence identity: 100
1a8r D - percentage of sequence identity: 100
1a8r E - percentage of sequence identity: 100
1a8r F - percentage of sequence identity: 100
1a8r G - percentage of sequence identity: 100
1a8r H - percentage of sequence identity: 100
1a8r I - percentage of sequence identity: 100
1a8r J - percentage of sequence identity: 100
1a8r K - percentage of sequence identity: 100
1a8r L - percentage of sequence identity: 100
1a8r M - percentage of sequence identity: 100
1a8r N - percentage of sequence identity: 100
1a8r O - percentage of sequence identity: 100
1a9c A - percentage of sequence identity: 99
1a9c B - percentage of sequence identity: 99
1a9c C - percentage of sequence identity: 99
1a9c D - percentage of sequence identity: 99
1a9c E - percentage of sequence identity: 99
1a9c F - percentage of sequence identity: 99
1a9c G - percentage of sequence identity: 99
1a9c H - percentage of sequence identity: 99
1a9c I - percentage of sequence identity: 99
1a9c J - percentage of sequence identity: 99
1a9c K - percentage of sequence identity: 99
1a9c L - percentage of sequence identity: 99
1a9c M - percentage of sequence identity: 99
1a9c N - percentage of sequence identity: 99
1a9c O - percentage of sequence identity: 99
1fbx A - percentage of sequence identity: 99
1fbx B - percentage of sequence identity: 99
1fbx C - percentage of sequence identity: 99
1fbx D - percentage of sequence identity: 99
1fbx E - percentage of sequence identity: 99
1fbx F - percentage of sequence identity: 99
1fbx G - percentage of sequence identity: 99
1fbx H - percentage of sequence identity: 99
1fbx I - percentage of sequence identity: 99
1fbx J - percentage of sequence identity: 99
1fbx K - percentage of sequence identity: 99
1fbx L - percentage of sequence identity: 99
1fbx M - percentage of sequence identity: 99
1fbx N - percentage of sequence identity: 99
1fbx O - percentage of sequence identity: 99
1gtp A - percentage of sequence identity: 99
1gtp B - percentage of sequence identity: 99
1gtp C - percentage of sequence identity: 99
1gtp D - percentage of sequence identity: 99
1gtp E - percentage of sequence identity: 99
1gtp F - percentage of sequence identity: 99
1gtp G - percentage of sequence identity: 99
1gtp H - percentage of sequence identity: 99
1gtp I - percentage of sequence identity: 99
1gtp J - percentage of sequence identity: 99
1gtp K - percentage of sequence identity: 99
1gtp L - percentage of sequence identity: 99
1gtp M - percentage of sequence identity: 99
1gtp N - percentage of sequence identity: 99
1gtp O - percentage of sequence identity: 99
1gtp P - percentage of sequence identity: 99
1gtp Q - percentage of sequence identity: 99
1gtp R - percentage of sequence identity: 99
1gtp S - percentage of sequence identity: 99
1gtp T - percentage of sequence identity: 99
1n3r A - percentage of sequence identity: 100
1n3r B - percentage of sequence identity: 100
1n3r C - percentage of sequence identity: 100
1n3r D - percentage of sequence identity: 100
1n3r E - percentage of sequence identity: 100
1n3r F - percentage of sequence identity: 100
1n3r G - percentage of sequence identity: 100
1n3r H - percentage of sequence identity: 100
1n3r I - percentage of sequence identity: 100
1n3r J - percentage of sequence identity: 100
1n3r K - percentage of sequence identity: 100
1n3r L - percentage of sequence identity: 100
1n3r M - percentage of sequence identity: 100
1n3r N - percentage of sequence identity: 100
1n3r O - percentage of sequence identity: 100
1n3s A - percentage of sequence identity: 99
1n3s B - percentage of sequence identity: 99
1n3s C - percentage of sequence identity: 99
1n3s D - percentage of sequence identity: 99
1n3s E - percentage of sequence identity: 99
1n3s F - percentage of sequence identity: 99
1n3s G - percentage of sequence identity: 99
1n3s H - percentage of sequence identity: 99
1n3s I - percentage of sequence identity: 99
1n3s J - percentage of sequence identity: 99
1n3t A - percentage of sequence identity: 99
1n3t B - percentage of sequence identity: 99
1n3t C - percentage of sequence identity: 99
1n3t D - percentage of sequence identity: 99
1n3t E - percentage of sequence identity: 99
1n3t F - percentage of sequence identity: 99
1n3t G - percentage of sequence identity: 99
1n3t H - percentage of sequence identity: 99
1n3t I - percentage of sequence identity: 99
1n3t J - percentage of sequence identity: 99
1n3t K - percentage of sequence identity: 99
1n3t L - percentage of sequence identity: 99
1n3t M - percentage of sequence identity: 99
1n3t N - percentage of sequence identity: 99
1n3t O - percentage of sequence identity: 99