PDB: 1aya Compound: Tyrosine phosphatase syp (n-terminal sh2 domain) ( Classification: HYDROLASE(SH2 DOMAIN) Entry date in PDB: 1994-08-31 Resolution [Å]: 2.05 R-Factor: 0.180

CHAIN: A SWISS-PROT/TREMBL: P35235    KEYWORD: 3D-structure    Hydrolase    Phosphorylation    Protein phosphatase    Repeat    SH2 domain    EC: 3.1.3.48 SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Tyrosine phosphatase Syp    Mouse (Mus musculus) GO:  phosphoprotein phosphatase activity    protein tyrosine phosphatase activity    intracellular signaling cascade    protein amino acid dephosphorylation    CHAIN: B SWISS-PROT/TREMBL: P35235    KEYWORD: 3D-structure    Hydrolase    Phosphorylation    Protein phosphatase    Repeat    SH2 domain    EC: 3.1.3.48 SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    Tyrosine phosphatase Syp    Mouse (Mus musculus) GO:  phosphoprotein phosphatase activity    protein tyrosine phosphatase activity    intracellular signaling cascade    protein amino acid dephosphorylation    CHAIN: P SWISS-PROT/TREMBL: P05622    KEYWORD: ATP-binding    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 GO:  membrane    ATP binding    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    vascular endothelial growth factor receptor activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway    CHAIN: Q SWISS-PROT/TREMBL: P05622    KEYWORD: ATP-binding    Glycoprotein    Immunoglobulin domain    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 GO:  membrane    ATP binding    protein kinase activity    protein-tyrosine kinase activity    transmembrane receptor protein tyrosine kinase activity    vascular endothelial growth factor receptor activity    protein amino acid phosphorylation    transmembrane receptor protein tyrosine kinase signaling pathway

Image Source: PDB

Loops in ArchDB40 clusters

1aya_A_13 - HE => SUBCLASS : 4.35.1
1aya_A_57 - HA => SUBCLASS : 3.3.1
1aya_A_28 - HA => SUBCLASS : 6.5.1

Loops in ArchDB95 clusters

1aya_A_13 - HE => SUBCLASS : 5.8.2
1aya_A_57 - HA => SUBCLASS : 3.6.1
1aya_A_28 - HA => SUBCLASS : 7.1.1

Loops not clustered in ArchDB

1aya_A_50 - AR
1aya_A_63 - EH
1aya_A_41 - HA
1aya_A_74 - HE

1aya A - percentage of sequence identity: 100
1aya B - percentage of sequence identity: 100
1ayb A - percentage of sequence identity: 100
1ayc A - percentage of sequence identity: 100
1ayd - - percentage of sequence identity: 100