PDB: 1bue Compound: imipenem-hydrolysing beta-lactamase Classification: HYDROLASE Entry date in PDB: 1999-09-02 Resolution [Å]: 1.64 R-Factor: 0.192

CHAIN: A SWISS-PROT/TREMBL: P52663    KEYWORD: 3D-structure    Antibiotic resistance    Hydrolase    Signal    EC: 3.5.2.6 SCOP: e.3.1.1 Multi-domain proteins (alpha and beta)    beta-lactamase/transpeptidase-like    beta-lactamase/transpeptidase-like    beta-Lactamase/D-ala carboxypeptidase    beta-Lactamase, class A    Enterobacter cloacae, NMC-A carbapenemase GO:  beta-lactamase activity    beta-lactam antibiotic catabolism    response to antibiotic

Image Source: PDB

Loops in ArchDB40 clusters

1bue_A_244 - HA => SUBCLASS : 5.4.1
1bue_A_43 - HA => SUBCLASS : 5.8.3
1bue_A_180 - EH => SUBCLASS : 1.1.1
1bue_A_66 - EH => SUBCLASS : 2.7.1
1bue_A_56 - AR => SUBCLASS : 5.28.1
1bue_A_119 - HH => SUBCLASS : 2.2.3
1bue_A_119 - HH => SUBCLASS : 2.2.5
1bue_A_132 - HH => SUBCLASS : 2.6.1

Loops in ArchDB95 clusters

1bue_A_180 - EH => SUBCLASS : 1.1.2
1bue_A_66 - EH => SUBCLASS : 2.7.1
1bue_A_259 - EH => SUBCLASS : 8.6.1
1bue_A_56 - AR => SUBCLASS : 5.10.1
1bue_A_119 - HH => SUBCLASS : 2.2.3
1bue_A_132 - HH => SUBCLASS : 2.6.1
1bue_A_183 - HH => SUBCLASS : 5.12.1
1bue_A_244 - HA => SUBCLASS : 5.3.1

Loops in ArchDB-EC clusters

1bue_A_183 - HH => SUBCLASS : 5.10.1

Loops not clustered in ArchDB

1bue_A_56 - AR
1bue_A_94 - EH
1bue_A_117 - EH
1bue_A_230 - HA
1bue_A_43 - HA
1bue_A_230 - HA
1bue_A_244 - HA
1bue_A_144 - HE
1bue_A_107 - HE
1bue_A_73 - HE
1bue_A_30 - HE
1bue_A_201 - HE

1bul - - percentage of sequence identity: 100
1dy6 B - percentage of sequence identity: 76