PDB: 1iar Compound: interleukin-4 Classification: CYTOKINE/RECEPTOR Entry date in PDB: 2000-03-03 Resolution [Å]: 2.30 R-Factor: 0.218

CHAIN: A SWISS-PROT/TREMBL: P05112    KEYWORD: 3D-structure    Alternative splicing    B-cell activation    Cytokine    Glycoprotein    Growth factor    Signal    SCOP: a.26.1.2 All alpha proteins    4-helical cytokines    4-helical cytokines    Short-chain cytokines    Interleukin-4 (IL-4)    Human (Homo sapiens) GO:  extracellular region    growth factor activity    hematopoietin/interferon-class (D200-domain) cytokine receptor binding    interleukin-4 receptor binding    immune response    CHAIN: B SWISS-PROT/TREMBL: P24394    KEYWORD: 3D-structure    Disease mutation    Glycoprotein    Polymorphism    Receptor    Signal    Transmembrane    SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Interleukin-4 receptor alpha chain    Human (Homo sapiens) SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Interleukin-4 receptor alpha chain    Human (Homo sapiens) GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Image Source: PDB

Loops in ArchDB40 clusters

1iar_B_29 - HE => SUBCLASS : 0.1.5
1iar_B_74 - HA => SUBCLASS : 2.3.4
1iar_B_147 - AR => SUBCLASS : 4.10.2
1iar_B_83 - AR => SUBCLASS : 10.5.1

Loops in ArchDB95 clusters

1iar_B_147 - AR => SUBCLASS : 4.20.2
1iar_B_147 - AR => SUBCLASS : 5.13.1
1iar_B_83 - AR => SUBCLASS : 10.10.1
1iar_B_29 - HE => SUBCLASS : 0.1.7
1iar_B_74 - HA => SUBCLASS : 2.3.2
1iar_B_74 - HA => SUBCLASS : 2.3.7
1iar_B_52 - HA => SUBCLASS : 3.5.1

Loops not clustered in ArchDB

1iar_B_114 - AR
1iar_B_158 - AR
1iar_B_47 - AR
1iar_B_58 - AR
1iar_B_16 - EH
1iar_B_102 - HA
1iar_B_133 - HA
1iar_B_32 - HA
1iar_B_172 - HA
1iar_B_3 - HA

null nu - percentage of sequence identity: 0