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Information on 1itw
PDB: 1itw
Compound: isocitrate dehydrogenase
Classification: OXIDOREDUCTASE
Entry date in PDB: 2002-12-11
Resolution [Å]: 1.95
R-Factor: 0.193


CHAIN: A
SWISS-PROT/TREMBL: P16100
   KEYWORD: 3D-structure    Glyoxylate bypass    NADP    Oxidoreductase    Phosphorylation    Tricarboxylic acid cycle   
EC: 1.1.1.42
SCOP: c.77.1.2 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Monomeric isocitrate dehydrogenase    Monomeric isocitrate dehydrogenase    Azotobacter vinelandii
GO:  isocitrate dehydrogenase (NADP+) activity    tricarboxylic acid cycle   


CHAIN: B
SWISS-PROT/TREMBL: P16100
   KEYWORD: 3D-structure    Glyoxylate bypass    NADP    Oxidoreductase    Phosphorylation    Tricarboxylic acid cycle   
EC: 1.1.1.42
SCOP: c.77.1.2 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Monomeric isocitrate dehydrogenase    Monomeric isocitrate dehydrogenase    Azotobacter vinelandii
GO:  isocitrate dehydrogenase (NADP+) activity    tricarboxylic acid cycle   


CHAIN: C
SWISS-PROT/TREMBL: P16100
   KEYWORD: 3D-structure    Glyoxylate bypass    NADP    Oxidoreductase    Phosphorylation    Tricarboxylic acid cycle   
EC: 1.1.1.42
SCOP: c.77.1.2 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Monomeric isocitrate dehydrogenase    Monomeric isocitrate dehydrogenase    Azotobacter vinelandii
GO:  isocitrate dehydrogenase (NADP+) activity    tricarboxylic acid cycle   


CHAIN: D
SWISS-PROT/TREMBL: P16100
   KEYWORD: 3D-structure    Glyoxylate bypass    NADP    Oxidoreductase    Phosphorylation    Tricarboxylic acid cycle   
EC: 1.1.1.42
SCOP: c.77.1.2 Alpha and beta proteins (a/b)    Isocitrate/Isopropylmalate dehydrogenase-like    Isocitrate/Isopropylmalate dehydrogenase-like    Monomeric isocitrate dehydrogenase    Monomeric isocitrate dehydrogenase    Azotobacter vinelandii
GO:  isocitrate dehydrogenase (NADP+) activity    tricarboxylic acid cycle   
1itw Image
Image Source: PDB

Stored Loops of 1itw

Loops in ArchDB40 clusters

1itw_A_229 - HE => SUBCLASS : 1.1.1
1itw_A_13 - HE => SUBCLASS : 1.1.1
1itw_A_229 - HE => SUBCLASS : 1.1.2
1itw_A_463 - HE => SUBCLASS : 1.1.2
1itw_A_229 - HE => SUBCLASS : 1.1.4
1itw_A_13 - HE => SUBCLASS : 2.2.2
1itw_A_521 - HE => SUBCLASS : 3.2.1
1itw_A_65 - HE => SUBCLASS : 4.5.1
1itw_A_566 - HA => SUBCLASS : 3.1.1
1itw_A_331 - HA => SUBCLASS : 4.1.1
1itw_A_331 - HA => SUBCLASS : 4.1.2
1itw_A_194 - HA => SUBCLASS : 4.2.1
1itw_A_433 - HA => SUBCLASS : 4.2.2
1itw_A_362 - HA => SUBCLASS : 5.1.3
1itw_A_433 - HA => SUBCLASS : 5.1.6
1itw_A_455 - EH => SUBCLASS : 1.1.8
1itw_A_455 - EH => SUBCLASS : 1.1.9
1itw_A_539 - EH => SUBCLASS : 1.1.18
1itw_A_370 - EH => SUBCLASS : 2.1.18
1itw_A_143 - EH => SUBCLASS : 2.2.6
1itw_A_36 - EH => SUBCLASS : 2.4.3
1itw_A_484 - EH => SUBCLASS : 4.1.1
1itw_A_172 - EH => SUBCLASS : 4.52.1
1itw_A_484 - EH => SUBCLASS : 5.14.1
1itw_A_207 - AR => SUBCLASS : 3.1.1
1itw_A_186 - AR => SUBCLASS : 3.2.9
1itw_A_207 - AR => SUBCLASS : 3.3.1
1itw_A_444 - AR => SUBCLASS : 4.1.2
1itw_A_186 - AR => SUBCLASS : 4.5.2
1itw_A_604 - HH => SUBCLASS : 2.2.1
1itw_A_720 - HH => SUBCLASS : 3.10.1

Loops in ArchDB95 clusters

1itw_A_539 - EH => SUBCLASS : 1.1.1
1itw_A_221 - EH => SUBCLASS : 1.1.7
1itw_A_455 - EH => SUBCLASS : 1.1.7
1itw_A_370 - EH => SUBCLASS : 2.1.9
1itw_A_143 - EH => SUBCLASS : 2.2.4
1itw_A_36 - EH => SUBCLASS : 2.3.3
1itw_A_484 - EH => SUBCLASS : 4.1.1
1itw_A_484 - EH => SUBCLASS : 4.1.5
1itw_A_172 - EH => SUBCLASS : 4.43.1
1itw_A_207 - AR => SUBCLASS : 2.3.1
1itw_A_444 - AR => SUBCLASS : 2.3.1
1itw_A_207 - AR => SUBCLASS : 3.3.1
1itw_A_444 - AR => SUBCLASS : 3.3.2
1itw_A_444 - AR => SUBCLASS : 3.5.5
1itw_A_186 - AR => SUBCLASS : 4.3.1
1itw_A_297 - HH => SUBCLASS : 2.1.21
1itw_A_604 - HH => SUBCLASS : 2.2.1
1itw_A_720 - HH => SUBCLASS : 3.12.1
1itw_A_181 - HE => SUBCLASS : 0.1.1
1itw_A_229 - HE => SUBCLASS : 1.1.1
1itw_A_13 - HE => SUBCLASS : 1.1.1
1itw_A_229 - HE => SUBCLASS : 1.2.2
1itw_A_463 - HE => SUBCLASS : 2.1.2
1itw_A_463 - HE => SUBCLASS : 3.2.1
1itw_A_65 - HE => SUBCLASS : 3.4.1
1itw_A_521 - HE => SUBCLASS : 3.5.1
1itw_A_135 - HE => SUBCLASS : 4.42.1
1itw_A_566 - HA => SUBCLASS : 3.1.1
1itw_A_194 - HA => SUBCLASS : 3.1.2
1itw_A_331 - HA => SUBCLASS : 4.1.1
1itw_A_433 - HA => SUBCLASS : 4.3.1
1itw_A_433 - HA => SUBCLASS : 5.1.1
1itw_A_362 - HA => SUBCLASS : 5.1.7
1itw_A_362 - HA => SUBCLASS : 5.4.1

Loops in ArchDB-EC clusters

1itw_A_720 - HH => SUBCLASS : 3.11.1

Loops not clustered in ArchDB

1itw_A_409 - AR
1itw_A_426 - AR
1itw_A_186 - AR
1itw_A_207 - AR
1itw_A_409 - AR
1itw_A_426 - AR
1itw_A_444 - AR
1itw_A_5 - EH
1itw_A_79 - EH
1itw_A_249 - EH
1itw_A_338 - EH
1itw_A_516 - EH
1itw_A_576 - EH
1itw_A_331 - HA
1itw_A_362 - HA
1itw_A_194 - HA
1itw_A_433 - HA
1itw_A_566 - HA
1itw_A_149 - HE
1itw_A_309 - HE
1itw_A_349 - HE
1itw_A_380 - HE
1itw_A_493 - HE
1itw_A_544 - HE
1itw_A_587 - HH
1itw_A_44 - HH
1itw_A_90 - HH
1itw_A_117 - HH
1itw_A_262 - HH
1itw_A_276 - HH
1itw_A_695 - HH
1itw_A_678 - HH
1itw_A_656 - HH
1itw_A_624 - HH
1itw_A_283 - HH

Homologous structures to 1itw classified in ArchDB

1itw A - percentage of sequence identity: 100
1itw B - percentage of sequence identity: 100
1itw C - percentage of sequence identity: 100
1itw D - percentage of sequence identity: 100
1j1w A - percentage of sequence identity: 100
1j1w B - percentage of sequence identity: 100
1j1w C - percentage of sequence identity: 100
1j1w D - percentage of sequence identity: 100
2b0t A - percentage of sequence identity: 62