PDB: 1l6s Compound: porphobilinogen synthase Classification: LYASE Entry date in PDB: 2002-04-17 Resolution [Å]: 1.70 R-Factor: 0.195

CHAIN: A SWISS-PROT/TREMBL: P15002    KEYWORD: 3D-structure    Complete proteome    Lyase    Magnesium    Porphyrin biosynthesis    Zinc    EC: 4.2.1.24 SCOP: c.1.10.3 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Aldolase    5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)    5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)    Escherichia coli GO:  porphobilinogen synthase activity    porphobilinogen synthase activity    heme biosynthesis    heme biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P15002    KEYWORD: 3D-structure    Complete proteome    Lyase    Magnesium    Porphyrin biosynthesis    Zinc    EC: 4.2.1.24 SCOP: c.1.10.3 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Aldolase    5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)    5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)    Escherichia coli GO:  porphobilinogen synthase activity    porphobilinogen synthase activity    heme biosynthesis    heme biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1l6s_A_44 - HA => SUBCLASS : 6.5.1
1l6s_A_307 - EH => SUBCLASS : 0.1.13
1l6s_A_307 - EH => SUBCLASS : 0.1.19
1l6s_A_53 - EH => SUBCLASS : 1.3.1
1l6s_A_160 - EH => SUBCLASS : 6.43.1
1l6s_A_187 - AR => SUBCLASS : 2.1.11
1l6s_A_272 - HH => SUBCLASS : 4.1.2
1l6s_A_272 - HH => SUBCLASS : 4.4.1

Loops in ArchDB95 clusters

1l6s_A_307 - EH => SUBCLASS : 0.1.24
1l6s_A_53 - EH => SUBCLASS : 1.2.1
1l6s_A_193 - EH => SUBCLASS : 3.1.17
1l6s_A_160 - EH => SUBCLASS : 6.42.1
1l6s_A_187 - AR => SUBCLASS : 2.1.2
1l6s_A_272 - HH => SUBCLASS : 4.1.1
1l6s_A_44 - HA => SUBCLASS : 7.1.1

Loops in ArchDB-EC clusters

1l6s_A_272 - HH => SUBCLASS : 4.1.1

Loops not clustered in ArchDB

1l6s_A_187 - AR
1l6s_A_30 - AR
1l6s_A_30 - AR
1l6s_A_74 - EH
1l6s_A_113 - EH
1l6s_A_243 - EH
1l6s_A_266 - EH
1l6s_A_44 - HA
1l6s_A_14 - HE
1l6s_A_289 - HE
1l6s_A_252 - HE
1l6s_A_225 - HE
1l6s_A_139 - HE
1l6s_A_97 - HE
1l6s_A_60 - HE
1l6s_A_170 - HE
1l6s_A_201 - HH

1b4e A - percentage of sequence identity: 99
1i8j A - percentage of sequence identity: 100
1i8j B - percentage of sequence identity: 100
1l6s A - percentage of sequence identity: 100
1l6s B - percentage of sequence identity: 100
1l6y A - percentage of sequence identity: 100
1l6y B - percentage of sequence identity: 100