PDB: 1omw Compound: g-protein coupled receptor kinase 2 Classification: TRANSFERASE Entry date in PDB: 2003-06-03 Resolution [Å]: 2.50 R-Factor: 0.216

CHAIN: A SWISS-PROT/TREMBL: P21146    KEYWORD: 3D-structure    ATP-binding    Multigene family    Serine/threonine-protein kinase    Transferase    EC: 2.7.1.126 SCOP: a.91.1.1 All alpha proteins    Regulator of G-protein signaling, RGS    Regulator of G-protein signaling, RGS    Regulator of G-protein signaling, RGS    G-protein coupled receptor kinase 2, N-terminal domain    Cow (Bos taurus) SCOP: b.55.1.1 All beta proteins    PH domain-like    PH domain-like    Pleckstrin-homology domain (PH domain)    G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1)    Cow (Bos taurus) SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    G-protein coupled receptor kinase 2    Cow (Bos taurus) GO:  ATP binding    G-protein coupled receptor kinase activity    protein kinase activity    protein serine/threonine kinase activity    signal transducer activity    protein amino acid phosphorylation    signal transduction    CHAIN: G SWISS-PROT/TREMBL: P16874    KEYWORD: 3D-structure    Acetylation    Lipoprotein    Multigene family    Prenylation    Transducer    SCOP: a.137.3.1 All alpha proteins    Non-globular all-alpha subunits of globular proteins    Transducin (heterotrimeric G protein), gamma chain    Transducin (heterotrimeric G protein), gamma chain    Transducin (heterotrimeric G protein), gamma chain    Cow (Bos taurus) GO:  heterotrimeric G-protein complex    signal transducer activity    G-protein coupled receptor protein signaling pathway

Image Source: PDB

Loops in ArchDB40 clusters

1omw_A_291 - HE => SUBCLASS : 1.1.3
1omw_A_577 - HA => SUBCLASS : 2.2.1
1omw_A_257 - HA => SUBCLASS : 2.2.3
1omw_A_191 - HA => SUBCLASS : 2.2.12
1omw_A_191 - HA => SUBCLASS : 2.2.33
1omw_A_323 - HA => SUBCLASS : 3.1.1
1omw_A_606 - HA => SUBCLASS : 3.10.2
1omw_A_618 - HA => SUBCLASS : 4.2.1
1omw_A_587 - HA => SUBCLASS : 5.4.1
1omw_A_511 - EH => SUBCLASS : 1.1.9
1omw_A_629 - EH => SUBCLASS : 2.1.2
1omw_A_629 - EH => SUBCLASS : 2.1.3
1omw_A_629 - EH => SUBCLASS : 2.1.11
1omw_A_266 - EH => SUBCLASS : 7.8.1
1omw_A_599 - AR => SUBCLASS : 3.4.1
1omw_A_331 - AR => SUBCLASS : 6.26.1
1omw_A_313 - AR => SUBCLASS : 8.2.1
1omw_A_160 - HH => SUBCLASS : 1.1.1
1omw_A_55 - HH => SUBCLASS : 1.1.3
1omw_A_55 - HH => SUBCLASS : 1.1.8
1omw_A_224 - HH => SUBCLASS : 1.3.2
1omw_A_80 - HH => SUBCLASS : 3.4.5
1omw_A_80 - HH => SUBCLASS : 3.6.1
1omw_A_80 - HH => SUBCLASS : 3.6.3
1omw_A_114 - HH => SUBCLASS : 6.6.1
1omw_A_444 - HH => SUBCLASS : 8.12.1

Loops in ArchDB95 clusters

1omw_A_511 - EH => SUBCLASS : 1.1.7
1omw_A_511 - EH => SUBCLASS : 1.1.14
1omw_A_629 - EH => SUBCLASS : 2.1.3
1omw_A_629 - EH => SUBCLASS : 3.3.1
1omw_A_266 - EH => SUBCLASS : 7.13.1
1omw_A_599 - AR => SUBCLASS : 3.2.2
1omw_A_331 - AR => SUBCLASS : 6.45.1
1omw_A_313 - AR => SUBCLASS : 8.5.1
1omw_A_160 - HH => SUBCLASS : 1.1.2
1omw_A_55 - HH => SUBCLASS : 1.1.3
1omw_A_55 - HH => SUBCLASS : 1.1.4
1omw_A_224 - HH => SUBCLASS : 1.3.2
1omw_A_80 - HH => SUBCLASS : 3.3.3
1omw_A_80 - HH => SUBCLASS : 3.5.1
1omw_G_9 - HH => SUBCLASS : 5.16.2
1omw_A_114 - HH => SUBCLASS : 6.1.1
1omw_A_444 - HH => SUBCLASS : 8.16.1
1omw_A_291 - HE => SUBCLASS : 1.2.1
1omw_A_577 - HA => SUBCLASS : 2.2.1
1omw_A_191 - HA => SUBCLASS : 2.2.1
1omw_A_257 - HA => SUBCLASS : 2.2.3
1omw_A_191 - HA => SUBCLASS : 2.2.13
1omw_A_323 - HA => SUBCLASS : 3.1.1
1omw_A_618 - HA => SUBCLASS : 3.1.2
1omw_A_587 - HA => SUBCLASS : 5.3.1

Loops in ArchDB-EC clusters

1omw_A_114 - HH => SUBCLASS : 6.11.1

Loops not clustered in ArchDB

1omw_A_331 - AR
1omw_A_313 - AR
1omw_A_599 - AR
1omw_A_216 - EH
1omw_A_340 - EH
1omw_A_561 - HA
1omw_A_191 - HA
1omw_A_204 - HA
1omw_A_257 - HA
1omw_A_587 - HA
1omw_A_323 - HA
1omw_A_606 - HA
1omw_A_561 - HA
1omw_A_577 - HA
1omw_A_204 - HA
1omw_A_618 - HA
1omw_A_169 - HE
1omw_A_233 - HE
1omw_A_458 - HE
1omw_A_526 - HE
1omw_A_514 - HH
1omw_A_40 - HH
1omw_A_62 - HH
1omw_A_98 - HH
1omw_A_126 - HH
1omw_A_147 - HH
1omw_A_279 - HH
1omw_A_359 - HH
1omw_A_371 - HH
1omw_A_399 - HH
1omw_A_419 - HH

1bak - - percentage of sequence identity: 97
1tbg A - percentage of sequence identity: 100
1ym7 A - percentage of sequence identity: 100
1ym7 B - percentage of sequence identity: 100
1ym7 C - percentage of sequence identity: 100
1ym7 D - percentage of sequence identity: 100
2bcj A - percentage of sequence identity: 100