PDB: 1toh Compound: tyrosine hydroxylase Classification: HYDROXYLASE Entry date in PDB: 1998-06-03 Resolution [Å]: 2.30 R-Factor: 0.211

CHAIN: - SWISS-PROT/TREMBL: P04177    KEYWORD: 3D-structure    Catecholamine biosynthesis    Iron    Monooxygenase    Neurotransmitter biosynthesis    Oxidoreductase    Phosphorylation    EC: 1.14.16.2 SCOP: d.178.1.1 Alpha and beta proteins (a+b)    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Tyrosine hydroxylase    Rat (Rattus norvegicus) GO:  iron ion binding    monooxygenase activity    tyrosine 3-monooxygenase activity    aromatic amino acid family metabolism    catecholamine biosynthesis

Image Source: PDB

Loops in ArchDB95 clusters

1toh_*_431 - EH => SUBCLASS : 2.1.4
1toh_*_466 - EH => SUBCLASS : 2.3.1
1toh_*_391 - HH => SUBCLASS : 1.1.1
1toh_*_337 - HH => SUBCLASS : 1.1.3
1toh_*_337 - HH => SUBCLASS : 1.1.57
1toh_*_343 - HH => SUBCLASS : 4.9.4
1toh_*_343 - HH => SUBCLASS : 4.9.6
1toh_*_250 - HH => SUBCLASS : 9.26.1
1toh_*_198 - HH => SUBCLASS : 13.5.1
1toh_*_361 - HE => SUBCLASS : 1.3.15
1toh_*_273 - HE => SUBCLASS : 2.1.5
1toh_*_273 - HE => SUBCLASS : 3.2.7
1toh_*_438 - HE => SUBCLASS : 4.8.4
1toh_*_397 - HE => SUBCLASS : 4.11.1
1toh_*_379 - HA => SUBCLASS : 2.1.1
1toh_*_457 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1toh_*_198 - HH => SUBCLASS : 13.1.1

Loops not clustered in ArchDB

1toh_*_287 - EH
1toh_*_308 - EH
1toh_*_385 - EH
1toh_*_409 - EH
1toh_*_379 - HA
1toh_*_457 - HA
1toh_*_297 - HE
1toh_*_415 - HE
1toh_*_227 - HH
1toh_*_329 - HH

1dmw A - percentage of sequence identity: 64
1j8t A - percentage of sequence identity: 63
1kw0 A - percentage of sequence identity: 63
1lrm A - percentage of sequence identity: 63
1mmk A - percentage of sequence identity: 63
1mmt A - percentage of sequence identity: 63
1pah - - percentage of sequence identity: 64
1phz A - percentage of sequence identity: 62
1tdw A - percentage of sequence identity: 63
1tg2 A - percentage of sequence identity: 63
2pah A - percentage of sequence identity: 60
2pah B - percentage of sequence identity: 60
2phm A - percentage of sequence identity: 62
2toh A - percentage of sequence identity: 99
3pah - - percentage of sequence identity: 64
4pah - - percentage of sequence identity: 64
5pah - - percentage of sequence identity: 64
6pah - - percentage of sequence identity: 64