PDB: 4fiv Compound: feline immunodeficiency virus protease Classification: ASPARTIC PROTEASE Entry date in PDB: 1999-01-13 Resolution [Å]: 1.80 R-Factor: 0.149

CHAIN: - SWISS-PROT/TREMBL: P16088    KEYWORD: 3D-structure    Aspartyl protease    Endonuclease    Hydrolase    Metal-binding    Nuclease    Nucleotide metabolism    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.50.1.1 All beta proteins    Acid proteases    Acid proteases    Retroviral protease (retropepsin)    Feline immunodeficiency virus (FIV) protease    Feline immunodeficiency virus GO:  aspartic-type endopeptidase activity    DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    dUTP metabolism    proteolysis and peptidolysis    RNA-dependent DNA replication

Image Source: PDB

Loops in ArchDB40 clusters

4fiv_*_15 - HA => SUBCLASS : 2.1.2
4fiv_*_15 - HA => SUBCLASS : 2.1.4
4fiv_*_62 - HA => SUBCLASS : 5.11.2
4fiv_*_101 - EH => SUBCLASS : 1.1.3
4fiv_*_101 - EH => SUBCLASS : 1.1.8
4fiv_*_23 - AR => SUBCLASS : 6.2.1
4fiv_*_23 - AR => SUBCLASS : 6.2.2

Loops in ArchDB95 clusters

4fiv_*_101 - EH => SUBCLASS : 1.1.7
4fiv_*_23 - AR => SUBCLASS : 4.7.1
4fiv_*_23 - AR => SUBCLASS : 6.20.1
4fiv_*_15 - HA => SUBCLASS : 2.1.3
4fiv_*_15 - HA => SUBCLASS : 2.1.4
4fiv_*_62 - HA => SUBCLASS : 5.10.2

Loops in ArchDB-EC clusters

4fiv_*_15 - HA => SUBCLASS : 2.4.4

Loops not clustered in ArchDB

4fiv_*_37 - AR
4fiv_*_84 - AR
4fiv_*_23 - AR
4fiv_*_37 - AR
4fiv_*_84 - AR
4fiv_*_49 - HA
4fiv_*_15 - HA
4fiv_*_49 - HA
4fiv_*_62 - HA

1b11 A - percentage of sequence identity: 100
1fiv A - percentage of sequence identity: 100
2fiv A - percentage of sequence identity: 99
2fiv B - percentage of sequence identity: 99
3fiv A - percentage of sequence identity: 98
3fiv B - percentage of sequence identity: 98
5fiv A - percentage of sequence identity: 99
6fiv A - percentage of sequence identity: 99