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Information on SUBCLASS 8.22.1
Subclass Accession number: 3499
Subclass: 8.22.1 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.3 (>75 %)  1.3.3 (>75 %)  1.3.3.12.6 (>75 %)  2.6.1 (>75 %)  
GO : GO:0004152 (>75 %)  GO:0004158 (>75 %)  GO:0016627 (>75 %)  GO:0016634 (>75 %)  
SCOP : 51395 (>75 %)  51396 (>75 %)  53382 (>75 %)  53383 (>75 %)  53417 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 68.5 +/- -18.8
Average RMSD (Å) : 0.133 +/- 0.058

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: GhAAGhDKpGEh
(φψ)-conformation: bpppgabaalaa
Pattern: [LV][G][IL][A][A][G][FL][D][K][DHN][G][E][AC][IV][D][AG][L][GY]
Conservation:-1.0601.287-0.725-0.054-0.0541.287-1.0411.2870.617-1.0981.2870.617-0.602-0.3891.287-1.041-0.054-1.552
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1d3g_A_921d3g   A92109VGIAAGFDKHGEAVDGLYEEE-TTSSTTSSSHHHHHbbxxpgabaavaaaaaaa
1f76_A_581f76   A5875LGLAAGLDKDGECIDALGEEE-TTSSTT---HHHHHxbxxxgaxaavaaaaaaa
1uum_A_921uum   A92109VGIAAGFDKNGEAVDGLYEEE-TTSSTTSSSHHHHHbbxxxgabaalaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1d3g_A_921d3g   A     FMNFLAVIN MONONUCLEOTIDE A - 95
1d3g_A_921d3g   A     FMNFLAVIN MONONUCLEOTIDE A - 96
1d3g_A_921d3g   A     FMNFLAVIN MONONUCLEOTIDE G - 97
1d3g_A_921d3g   A     BRE2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARBOXYLIC ACID F - 98
1d3g_A_921d3g   A     FMNFLAVIN MONONUCLEOTIDE F - 98
1d3g_A_921d3g   A     FMNFLAVIN MONONUCLEOTIDE K - 100
1d3g_A_921d3g   A     OROOROTIC ACID K - 100
1d3g_A_921d3g   A     BRE2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARBOXYLIC ACID M - 111
1f76_A_581f76   A     FMNFLAVIN MONONUCLEOTIDE A - 61
1f76_A_581f76   A     FMNFLAVIN MONONUCLEOTIDE A - 62
1f76_A_581f76   A     FMNFLAVIN MONONUCLEOTIDE G - 63
1f76_A_581f76   A     FMNFLAVIN MONONUCLEOTIDE L - 64
1f76_A_581f76   A     MSESELENOMETHIONINE K - 66
1f76_A_581f76   A     FMNFLAVIN MONONUCLEOTIDE K - 66
1f76_A_581f76   A     OROOROTIC ACID K - 66
1f76_A_581f76   A     MSESELENOMETHIONINE D - 72
1f76_A_581f76   A     MSESELENOMETHIONINE A - 73
1f76_A_581f76   A     MSESELENOMETHIONINE L - 74
1f76_A_581f76   A     MSESELENOMETHIONINE G - 75
1uum_A_921uum   A     AFI2-[4-(4-CHLOROPHENYL)CYCLOHEXYLIDENE]-3,4-DIHYDROXY-1(2H)-NAPHTHALENONE G - 97
1uum_A_921uum   A     AFI2-[4-(4-CHLOROPHENYL)CYCLOHEXYLIDENE]-3,4-DIHYDROXY-1(2H)-NAPHTHALENONE F - 98
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1uum_A_921uum   A AC1FMN BINDING SITE FOR CHAIN AA - 95
1uum_A_921uum   A AC1FMN BINDING SITE FOR CHAIN AA - 96
1uum_A_921uum   A AC3AFI BINDING SITE FOR CHAIN AF - 98

Clusters included in this Subclass
CLUSTER: EH.9.60