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Information on SUBCLASS 3.25.1
Subclass Accession number: 1227
Subclass: 3.25.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 4.2 (>75 %)  4.2.1 (>75 %)  4.2.1.10
GO : GO:0003855 (>75 %)  GO:0005524 (>75 %)  GO:0016835 (>75 %)  GO:0016836 (>75 %)  
SCOP : 51430 (>75 %)  51431 (>75 %)  52171 (>75 %)  52304 (>75 %)  52305 (>75 %)  
 Number of loops: 7

Average sequence ID (%) : 15.2 +/- 18.1
Average RMSD (Å) : 0.586 +/- 0.261

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 135-180 rho (°): 225-270
Consensus Sequence: hppXXXX
(φψ)-conformation: bblbpaa
Pattern: [ILTVW][AGKN][ITV][AES][GNRT]x[dnpst]xxx[GIKLV]
Conservation:0.1710.6981.6241.3900.844-1.166-0.463-0.885-1.110-0.597-0.506
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1exb_A_1821exb   A185195WGTSRWSSMEIEEEES--HHHHbbbbvxxaaaa
1gl4_A_4381gl4   A441451TAISTIPETVGEEEES--HHHHbbbbvbpaaaa
1hw6_A_1331hw6   A136146IGVSNHLVPHLEEEES--HHHHbbbblxxaaaa
1jo0_A_471jo0   A5060VKVAGADRETKEEETT--HHHHbxbxvbxaaaa
1lqa_A_1731lqa   A176186IGVSNETAFGVEEEES--HHHHbbbblbbaaaa
1us0_A_1561us0   A156166IGISNFNHLQVEEEES--HHHHbbbbvxxaaaa
1via_A_1441via   A146156LNIENKNIDELEE-TT--HHHHbxaxlbxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1exb_A_1821exb   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 188
1exb_A_1821exb   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 189
1hw6_A_1331hw6   A     MGMAGNESIUM ION E - 147
1jo0_A_471jo0   A     GOLGLYCEROL L - 47
1jo0_A_471jo0   A     GOLGLYCEROL K - 49
1jo0_A_471jo0   A     GOLGLYCEROL K - 51
1jo0_A_471jo0   A     GOLGLYCEROL Q - 61
1jo0_A_471jo0   A     GOLGLYCEROL I - 64
1jo0_A_471jo0   A     GOLGLYCEROL N - 65
1jo0_A_471jo0   A     GOLGLYCEROL A - 66
1jo0_A_471jo0   A     GOLGLYCEROL V - 68
1jo0_A_471jo0   A     GOLGLYCEROL R - 69
1lqa_A_1731lqa   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 179
1lqa_A_1731lqa   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 180
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 159
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 160
1us0_A_1561us0   A     LDTIDD594 N - 160
1us0_A_1561us0   A     CITCITRIC ACID F - 161
1us0_A_1561us0   A     CITCITRIC ACID N - 162
1us0_A_1561us0   A     CITCITRIC ACID H - 163
1us0_A_1561us0   A     CITCITRIC ACID L - 164
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AN - 162
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AH - 163

Clusters included in this Subclass
CLUSTER: EH.3.275
CLUSTER: EH.4.83