ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 8.4.1

Subclass Accession number: 146
Subclass: 8.4.1
Type: HE alpha-beta
DB: ArchDB-KI

Number of loops: 3

Average sequence ID (%) : 25.3 +/- 0.7
Average RMSD (Å) : 0.41 +/- 0.00

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 90-135

rho (°): 135-180

Consensus Sequence:	XhXGhXXIhphX
(φψ)-conformation:	aapgpplbppba

Pattern:	[IL]	[HKR]	x	[E]	x	[KR]	[IT]	[LY]	[KQ]	x	[LM]	x	[G]	[CG]	x	[GN]	[I]	[PV]	[KNT]	[ILV]	x	x	[CFI]	[GV]	x
Conservation:	0.547	-0.043	-1.683	1.909	-1.214	0.940	-0.318	0.383	0.591	-0.902	0.654	-0.824	2.612	-0.025	-0.824	0.636	1.206	0.054	-0.512	0.269	-1.136	-0.512	-0.590	-0.550	-0.668

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a6o_*_75	1a6o	-	78	102	IKREIKILQNLCGGPNIVKLLDIVR	HHHHHHHHHHHTTSTTB--EEEEEE	aaaaaaaaaaapgxxlbpxxabbbb
1cki_A_52	1cki	A	52	76	LHIESKIYKMMQGGVGIPTIRWCGA	HHHHHHHHHHSTTSTT---EEEEEE	aaaaaaaaaaapgxxvbxxxabbeb
2csn_*_52	2csn	-	52	76	LRDEYRTYKLLAGCTGIPNVYYFGQ	HHHHHHHHHHHTT-TT---EEEEEE	aaaaaaaaaaapvxxvbxxbabbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
2csn_*_52	2csn	*	CKIN-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE	E - 55
2csn_*_52	2csn	*	CKIN-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE	Y - 59
2csn_*_52	2csn	*	CKIN-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE	P - 69

Bibliographic annotations

Loop	PDB	Chain	Annotation	Residue
1cki_A_52	1cki RefK.L.LONGENECKER,P.J.ROACH,T.D.HURLEY. THREE DIMENSIONAL STRUCTURE OF MAMMALIAN CASEIN KINASE I: MOLECULAR BASIS FOR PHOSPHATE RECOGNITION J. MOL. BIOL. v.257;618,1996	A	ATP BINDING RESIDUE(VIA-WATER)	E - 55
1cki_A_52	1cki RefK.L.LONGENECKER,P.J.ROACH,T.D.HURLEY. THREE DIMENSIONAL STRUCTURE OF MAMMALIAN CASEIN KINASE I: MOLECULAR BASIS FOR PHOSPHATE RECOGNITION J. MOL. BIOL. v.257;618,1996	A	ATP BINDING RESIDUE(VIA-WATER)	Y - 59

Clusters included in this Subclass