ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.19.1

Subclass Accession number: 1484
Subclass: 6.19.1

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 3.2 (>75 %)  3.2.1 (>75 %)
GO : GO:0004553 (>75 %)  GO:0016160 (>75 %)  GO:0016798 (>75 %)
SCOP : 51445 (>75 %)  51446 (>75 %)  51604 (>75 %)  51609 (>75 %)

Number of loops: 5

Average sequence ID (%) : 28.0 +/- 21.3
Average RMSD (Å) : 0.520 +/- 0.084

Consensus geometry

d (Å): 15

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	hDhNphWphX
(φψ)-conformation:	bballabpaa

Pattern:	[gkrs]	[ILV]	[rt]	[LV]	[D]	[APVY]	[N]	[GQR]	[agy]	[LW]	[DRST]	x	[knps]	[AEKQ]	[AG]	[iv]	[KQRT]	[afi]	[acgs]	[KQR]
Conservation:	-0.707	0.412	-0.282	0.324	2.124	-0.832	2.124	-0.180	-0.637	1.929	-0.558	-0.901	-0.998	-0.210	0.362	-0.257	-0.186	-0.978	-0.894	0.345

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ec7_A_231	1ec7	A	231	250	RITLDPNGAWSLNEAIKIGK	EEEEE-TT-B-HHHHHHHHH	xbbbbavvaxxaaaaaaaaa
1jpm_A_187	1jpm	A	187	206	KLRLDANQGWRPKEAVTAIR	EEEEE-TT-S-HHHHHHHHH	xbbbballabxaaaaaaaaa
1muc_A_194	1muc	A	194	213	SVRVDVNQYWDESQAIRACQ	EEEEE-TT-B-HHHHHHHHH	xbbbbalvaxxaaaaaaaaa
1r6w_A_156	1r6w	A	157	176	HLRLDANRAWTPLKGQQFAK	EEEEE-TT-B-HHHHHHHHH	bbxbballabxaaaaaaaaa
2mnr_*_191	2mnr	-	191	210	GIMVDYNQSLDVPAAIKRSQ	EEEEE-TT-S-HHHHHHHHH	xbxbbalvabxaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ec7_A_231	1ec7	A	MGMAGNESIUM ION	D - 235
1ec7_A_231	1ec7	A	MGMAGNESIUM ION	N - 237
1jpm_A_187	1jpm	A	MGMAGNESIUM ION	D - 191
1jpm_A_187	1jpm	A	MGMAGNESIUM ION	N - 193
1muc_A_194	1muc	A	MNMANGANESE (II) ION	D - 198
1muc_A_194	1muc	A	MNMANGANESE (II) ION	N - 200
1r6w_A_156	1r6w	A	1642-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID	R - 159
1r6w_A_156	1r6w	A	MGMAGNESIUM ION	D - 161
1r6w_A_156	1r6w	A	1642-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID	D - 161
1r6w_A_156	1r6w	A	MGMAGNESIUM ION	N - 163
1r6w_A_156	1r6w	A	1642-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID	N - 163
2mnr_*_191	2mnr	*	MNMANGANESE (II) ION	D - 195
2mnr_*_191	2mnr	*	MNMANGANESE (II) ION	N - 197

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1muc_A_194	1muc	A	MNARESIDUES INVOLVED IN THE COORDINATION OF MN-ION IN CHAIN A.	D - 198

Clusters included in this Subclass

CLUSTER: EH.5.80