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Information on SUBCLASS 7.11.1
Subclass Accession number: 1972
Subclass: 7.11.1 PSSM
Type: AR beta-beta link
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.5 (>50 %)  1.5.1 (>50 %)  1.5.1.35.2 (>75 %)  5.2.1 (>75 %)  5.2.1.8
GO : GO:0003755 (>50 %)  GO:0004146 (>50 %)  GO:0004175 (>75 %)  GO:0004190 (>75 %)  GO:0008233 (>75 %)  GO:0016645 (>50 %)  GO:0016646 (>50 %)  GO:0016853 (>50 %)  GO:0016859 (>50 %)  
SCOP : 50629 (>75 %)  50630 (>75 %)  50646 (>75 %)  53596 (>50 %)  53597 (>50 %)  53598 (>50 %)  54533 (>75 %)  54534 (>75 %)  54535 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 25.0 +/- 23.7
Average RMSD (Å) : 0.667 +/- 0.208

Consensus geometry
d (Å): 15 delta (°): 90-135 theta (°): 90-135 rho (°): 225-270
Consensus Sequence: RhXXXhXXpXX
(φψ)-conformation: bpabpbpbabb
Pattern: [QT][R][IL][AEM]x[DPS][AF][AE][AGS][DT][AT]x
Conservation:0.1492.2650.860-0.927-1.663-0.354-0.0510.033-0.1080.4170.386-1.009
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1gmu_A_61gmu   A617QRLEIPAAATASEE-SS----SEEbbxabxbpxabb
1kmv_A_1311kmv   A136147TRIMQDFESDTFEEESS----SEExxxabxbpbabb
3dfr_*_1123dfr   -116127TRLAGSFEGDTKEEESS----SEEbbxaxbbxbabb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1kmv_A_1311kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE F - 134
1kmv_A_1311kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE T - 136
1kmv_A_1311kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 145
1kmv_A_1311kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 146
3dfr_*_1123dfr   *     MTXMETHOTREXATE L - 114
3dfr_*_1123dfr   *     MTXMETHOTREXATE V - 115
3dfr_*_1123dfr   *     MTXMETHOTREXATE T - 116
3dfr_*_1123dfr   *     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 125
3dfr_*_1123dfr   *     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 126

Clusters included in this Subclass
CLUSTER: AR.7.68