Information on SUBCLASS 1.2.23 |
Subclass Accession number: 2101
Subclass: 1.2.23 Type: HH alpha-alpha DB: ArchDB40 Image coordinates: Consensus coordinates: Conserved Annotation GO : GO:0005489 (>75 %) GO:0005515 (>75 %) SCOP : 46625 (>75 %) 46626 (>75 %) 46627 (>75 %) |
Number of loops: 4 Average sequence ID (%) : 10.2 +/- 11.4 Average RMSD (Å) : 0.525 +/- 0.222 Consensus geometry
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Consensus Sequence: | XXpPX |
(φψ)-conformation: | aabaa |
Pattern: | [LPT] | [AILV] | x | x | x | [EFKL] | [AENQ] | [KNQY] | [P] | x | [EFMR] | x | [ENY] | x | [AFL] | x | x | x |
Conservation: | -0.242 | 0.332 | -0.461 | 0.142 | -0.541 | -0.620 | 0.015 | -0.025 | 3.823 | -0.541 | -0.501 | -0.346 | 0.174 | -0.065 | 0.081 | -0.342 | -0.660 | -0.223 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1dvk_A_157 | 1dvk | A | 165 | 182 | TVLYHLQQPKEINLAVQS | HHHHHHTSGGGHHHHHHH | aaaaaaabaaaaaaaaaa |
1lh0_A_1184 | 1lh0 | A | 1187 | 1204 | LIAYLEEKPDMAEHLAAV | HHHHHHH-GGGHHHHHHH | aaaaaaaxaaaaaaaaaa |
1qus_A_174 | 1qus | A | 178 | 195 | LATLSFNYPRRAEYFSGE | HHHHHHS-GGGHHHHHHH | aaaaaaabaaaaaaaaaa |
1vj5_A_369 | 1vj5 | A | 369 | 386 | PLESIKANPVFDYQLYFQ | HHHHHHT-GGGHHHHHHH | aaaaaaabaaaaaaaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1qus_A_174 | 1qus | A | EDO1,2-ETHANEDIOL | R - 188 |
1qus_A_174 | 1qus | A | BCNBICINE | Y - 191 |
1qus_A_174 | 1qus | A | EDO1,2-ETHANEDIOL | Y - 191 |
1qus_A_174 | 1qus | A | EDO1,2-ETHANEDIOL | F - 192 |
1vj5_A_369 | 1vj5 | A | CIUN-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA | F - 379 |
1vj5_A_369 | 1vj5 | A | CIUN-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA | Y - 381 |
1vj5_A_369 | 1vj5 | A | CIUN-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA | Q - 382 |
1vj5_A_369 | 1vj5 | A | CIUN-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA | F - 385 |
Clusters included in this Subclass |
CLUSTER: HH.5.85 |