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Information on SUBCLASS 3.2.25
Subclass Accession number: 2299
Subclass: 3.2.25 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0003746 (>50 %)  GO:0008135 (>50 %)  
SCOP : 54712 (>50 %)  54713 (>50 %)  54714 (>50 %)  
 Number of loops: 3

Average sequence ID (%) : 17.2 +/- 27.7
Average RMSD (Å) : 0.867 +/- 0.208

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: pXcXXpX
(φψ)-conformation: aalppaa
Pattern: [ERY]x[ILV]xxxx[AL][LMT][KNQ]x[GN][AK][PT][EKQ][EPQ]x[AR][ET][AK][IM][AKV][EK][GI][QR]x[CK][KY][FVY]x[EGN][EG][LV]
Conservation:-0.809-0.2341.104-0.936-1.446-1.574-0.936-0.107-0.1710.339-1.3191.6410.3141.3350.9770.212-1.0250.0720.4930.3141.624-1.0641.589-0.9091.589-1.3190.1100.3020.467-1.446-0.2990.1230.990
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1efu_B_1871efu   B194226YQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHHHaaaaaaaaaaavpxaaaaaaaaaaaaaaaaaaa
1puo_A_221puo   A2254ELLLDLSLTKVNATEPERTAMKKIQDCYVENGLHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHHHaaaaaaaaaaalxxaaaaaaaaaaaaaaaaaea
1tfe_*_1151tfe   -122154RQIYIQAALNEGKPQQIAEKIAEGRLKKYLEEVHHHHHHHHHTTT--HHHHHHHHHHHHHHHHHHHaaaaaaaaaaavxxaaaaaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL M - 42
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL I - 45
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL Y - 49
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL R - 57
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL V - 58
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL D - 60
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL G - 61
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL L - 62
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL M - 64
1puo_A_221puo   A     MPD2-METHYL-2,4-PENTANEDIOL T - 65

Clusters included in this Subclass
CLUSTER: HH.4.217