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Information on SUBCLASS 6.12.1
Subclass Accession number: 2498
Subclass: 6.12.1 PSSM
Type: HH alpha-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0004180 (>50 %)  GO:0004246 (>50 %)  GO:0004857 (>75 %)  GO:0004859 (>75 %)  GO:0005509 (>75 %)  GO:0005543 (>75 %)  GO:0005544 (>75 %)  GO:0008233 (>50 %)  GO:0008237 (>50 %)  GO:0008238 (>50 %)  GO:0008241 (>50 %)  GO:0008270 (>50 %)  GO:0008289 (>75 %)  GO:0016462 (>75 %)  GO:0016817 (>75 %)  GO:0016818 (>75 %)  GO:0019834 (>75 %)  GO:0046914 (>50 %)  
SCOP : 47873 (>75 %)  47874 (>75 %)  47875 (>75 %)  51734 (>75 %)  51735 (>75 %)  55485 (>50 %)  55486 (>50 %)  55505 (>50 %)  
 Number of loops: 4

Average sequence ID (%) : 41.7 +/- 21.1
Average RMSD (Å) : 0.400 +/- 0.082

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: AhpGhGTcEX
(φψ)-conformation: aapebebpaa
Pattern: [APV][ASV]xx[AC][EK][AQR][IL][HKQR][KR][AS][FILM][KRS][G][AIW][G][T][DN][E]x[ALMT][IL]x[DERS][I][LM]
Conservation:-0.777-0.827-1.150-0.6920.1310.413-0.6140.342-0.4370.6660.080-0.437-0.3032.037-1.2172.0371.4460.5601.446-1.619-0.9910.335-0.840-0.8430.8560.398
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1axn_*_211axn   -2146PSVDAEAIQKAIRGIGTDEKMLISILHHHHHHHHHHHHSSSS--HHHHHHHHaaaaaaaaaaaapexebxaaaaaaaa
1axn_*_2351axn   -252277PAFLAERLHRALKGIGTDEFTLNRIMHHHHHHHHHHHHSSSS--HHHHHHHHaaaaaaaaaaaaxebMxxaaaaaaaa
1axn_*_921axn   -93118AVFDAKQLKKSMKGAGTNEDALIEILHHHHHHHHHHHH-SSS--HHHHHHHHaaaaaaaaaaaaxexebxaaaaaaaa
1n00_A_181n00   A1843VSEDCEQLRKAFSGWGTNEGLIIDILHHHHHHHHHHHTSSSS--HHHHHHHHaaaaaaaaaaaaxebebbaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1axn_*_211axn   *     CACALCIUM ION A - 31
1axn_*_211axn   *     CACALCIUM ION I - 32
1axn_*_211axn   *     CACALCIUM ION R - 33
1axn_*_211axn   *     CACALCIUM ION G - 34
1axn_*_211axn   *     CACALCIUM ION I - 35
1axn_*_211axn   *     CACALCIUM ION G - 36
1axn_*_211axn   *     CACALCIUM ION T - 37
1axn_*_921axn   *     CACALCIUM ION S - 103
1axn_*_921axn   *     CACALCIUM ION M - 104
1axn_*_921axn   *     CACALCIUM ION K - 105
1axn_*_921axn   *     CACALCIUM ION G - 106
1axn_*_921axn   *     CACALCIUM ION A - 107
1axn_*_921axn   *     CACALCIUM ION G - 108
1axn_*_921axn   *     CACALCIUM ION T - 109
1axn_*_2351axn   *     CACALCIUM ION G - 235
1axn_*_2351axn   *     CACALCIUM ION E - 238

Clusters included in this Subclass
CLUSTER: HH.6.75