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Information on SUBCLASS 4.12.1
Subclass Accession number: 299
Subclass: 4.12.1 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.2 (>50 %)  3.2.1 (>50 %)  3.2.1.2
GO : GO:0004553 (>50 %)  GO:0016160 (>50 %)  GO:0016798 (>50 %)  
SCOP : 51445 (>50 %)  51446 (>50 %)  
 Number of loops: 8

Average sequence ID (%) : 20.2 +/- 18.6
Average RMSD (Å) : 0.688 +/- 0.136

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: XhGXpphX
(φψ)-conformation: aaeaaabb
Pattern: x[AEKNQS][ADENQT][ailv][agikl]x[ailt][fhv][G][aekqs][DEGS][gkns][CILV]x
Conservation:-0.407-0.046-0.111-0.195-0.957-0.719-0.467-0.1273.095-0.4590.4370.3500.487-0.881
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ax4_A_1691ax4   A172185LKENIAQHGADNIVHHHHHHHH-GGGEEaaaaaaaaMaaaxa
1cex_*_521cex   -5669ASNLESAFGKDGVWHHHHHHHH-TTTEEaaaaaaaaeaaabb
1f0x_A_101f0x   A1326LNELARLVGSSHLLHHHHHHHH-GGGEEaaaaaaaaeaaabb
1j5p_A_1641j5p   A166179ASTIGLIVGFEKVKHHHHHHHH-GGGEEaaaaaaaaeaaabb
1jnr_A_1531jnr   A158171AEAAKMAVGEENIYHHHHHHHH-GGGEEaaaaaaaaMaaabb
1jtg_B_181jtg   B1831RQQVLDIAGAENCEHHHHHHHH-GGGEEaaaaaaaaMaaabb
1jtg_B_971jtg   B97110RAQVLATVGQGSCTHHHHHHHH-TBSEEaaaaaaaaeaaabb
1qlt_A_181qlt   A2538IQDIIRIVGSENVEHHHHHHHH-GGGEEaaaaaaaaeaaabb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ax4_A_1691ax4   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) T - 190
1j5p_A_1641j5p   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 164
1j5p_A_1641j5p   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 165
1j5p_A_1641j5p   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 168
1jnr_A_1531jnr   A     FADFLAVIN-ADENINE DINUCLEOTIDE Y - 153
1jnr_A_1531jnr   A     FADFLAVIN-ADENINE DINUCLEOTIDE K - 154

Clusters included in this Subclass
CLUSTER: HE.3.146
CLUSTER: HE.5.47