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Information on SUBCLASS 4.48.1
Subclass Accession number: 342
Subclass: 4.48.1 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0004802 (>75 %)  GO:0005509 (>75 %)  GO:0016744 (>75 %)  GO:0016829 (>75 %)  
SCOP : 52517 (>75 %)  52518 (>75 %)  88735 (>75 %)  88749 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 9.5 +/- 10.3
Average RMSD (Å) : 0.633 +/- 0.058

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: hppXGXXX
(φψ)-conformation: aappepbb
Pattern: x[AKN]x[ATV][FLM][ENT][HS]x[G]xx[ADK][ILV][FIY]
Conservation:-0.856-0.493-0.493-0.2030.233-0.1301.113-0.5662.774-0.711-1.002-0.6390.5960.378
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1kmo_A_941kmo   A94107ENDVFEHAGARDVIHHHHHT-SS-EEEEaaaaaaxxexbbbb
1kmv_A_1181kmv   A121134YKEAMNHPGHLKLFHHHHHTS-S-EEEEaaaaaaxxexbbbx
1pam_A_3391pam   A346359LAFTLTSRGVPAIYHHHHHHSSSEEEEEaaaaaaxxebwbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1kmv_A_1181kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 118
1kmv_A_1181kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 119
1kmv_A_1181kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 120
1kmv_A_1181kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE Y - 121
1kmv_A_1181kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Y - 121
1kmv_A_1181kmv   A     DMSDIMETHYL SULFOXIDE Y - 121
1kmv_A_1181kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 123
1kmv_A_1181kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE F - 134
1kmv_A_1181kmv   A     LII(Z)-6-(2-[2,5-DIMETHOXYPHENYL]ETHEN-1-YL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE T - 136

Clusters included in this Subclass
CLUSTER: HE.4.172