ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.12.1

Subclass Accession number: 3432
Subclass: 7.12.1

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 6

Average sequence ID (%) : 51.8 +/- 23.8
Average RMSD (Å) : 0.433 +/- 0.137

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 90-135

rho (°): 180-225

Consensus Sequence:	FphGXXpVIpG
(φψ)-conformation:	bbplalabpaa

Pattern:	[FL]	[KQS]	[CF]	[dknr]	[ILV]	[G]	[kv]	[GQ]	[EKNQ]	[V]	[I]	[KR]	[AG]	[FW]	[DE]	x	[AG]
Conservation:	0.170	-0.750	-0.057	-1.422	-0.175	1.824	-1.259	-0.502	-0.628	0.620	0.620	0.341	0.192	2.059	0.620	-1.489	-0.164

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bkf_*_46	1bkf	-	46	62	FKFMLGKQEVIRGWEEG	EEEETTSS-S-HHHHHH	xbbbxvalabxaaaaaa
1c9h_A_46	1c9h	A	46	62	FKFRIGKQEVIKGFEEG	EEEETTTT-S-HHHHHH	bbbxxvalabpaaaaaa
1n1a_A_77	1n1a	A	77	93	FSFDLGKGEVIKAWDIA	EEEETTTT-S-HHHHHH	xbbxxvavabpaaaaaa
1pbk_*_162	1pbk	-	162	178	LSFKVGVGKVIRGWDEA	EEEETTTTSS-HHHHHH	xbbbxvavabpaaaaaa
1r9h_A_60	1r9h	A	60	76	FSFNLGRGNVIKGWDLG	EEEETTTTSS-HHHHHH	xbbxxvavabpaaaaaa
1yat_*_46	1yat	-	46	62	FQCNIGVGQVIKGWDVG	EEEETTSSSS-HHHHHH	xbbxxvavabpaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	F - 46
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	Q - 53
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	E - 54
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	V - 55
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	I - 56
1bkf_*_46	1bkf	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	W - 59
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	F - 46
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	K - 47
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	R - 49
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	K - 52
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	Q - 53
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	E - 54
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	V - 55
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	I - 56
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	K - 57
1c9h_A_46	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	F - 59
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	L - 162
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	S - 163
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	F - 164
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	K - 165
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	V - 168
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	G - 169
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	K - 170
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	V - 171
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	I - 172
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	R - 173
1pbk_*_162	1pbk	*	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	W - 175
1yat_*_46	1yat	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	G - 53
1yat_*_46	1yat	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	Q - 54

Clusters included in this Subclass

CLUSTER: EH.6.87