ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.1.21

Subclass Accession number: 4521
Subclass: 2.1.21

PSSM

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 6

Average sequence ID (%) : 13.0 +/- 21.7
Average RMSD (Å) : 0.733 +/- 0.225

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	pphpXX
(φψ)-conformation:	aappaa

Pattern:	[adgkn]	[ADEK]	[ALVW]	[cesy]	[AEGQR]	[eqrw]	[efl]	[EHKR]	x	[lmv]	[DPS]	x	[denw]	x	x	[DHKR]	[EKR]	[AIKL]	[glv]
Conservation:	-1.282	0.847	-0.134	-1.012	-0.128	-0.982	-0.710	1.739	-0.748	0.720	1.311	-0.172	-0.449	-0.328	-0.501	0.945	2.130	-0.127	-1.120

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1fx7_A_94	1fx7	A	99	117	AEACRWEHVMSEDVERRLV	HHHHHHTTT--HHHHHHHH	aaaaaaaaaxxaaaaaaaa
1g3s_A_97	1g3s	A	99	117	DEASRWEHVMSDEVERRLV	HHHHHHTTT--HHHHHHHH	aaaaaaaaaxxaaaaaaaa
1itw_A_297	1itw	A	298	316	GDLYARIKTLPEAKQKEIE	HHHHHHGGGS-HHHHHHHH	aaaaaaaaaxwaaaaaaaa
1m3q_A_222	1m3q	A	222	240	LAWLQQLRESSYEEAHKAL	HHHHHHTTTS-HHHHHHHH	aaaaaaaaaxxaaaaaaaa
1nz0_A_90	1nz0	A	90	108	KKLSEEFERVDFWTVREKL	HHHHHHGGGS-HHHHHHHH	aaaaaaaaaxxaaaaaaaa
1on2_A_91	1on2	A	96	114	NDVEGIEHHLSWNSIDRIG	HHHHHHGGGS-HHHHHHHH	aaaaaaaaabxaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1fx7_A_94	1fx7	A	COCOBALT (II) ION	V - 97
1fx7_A_94	1fx7	A	COCOBALT (II) ION	H - 98
1fx7_A_94	1fx7	A	COCOBALT (II) ION	A - 101
1fx7_A_94	1fx7	A	COCOBALT (II) ION	C - 102
1fx7_A_94	1fx7	A	COCOBALT (II) ION	R - 103
1fx7_A_94	1fx7	A	COCOBALT (II) ION	E - 105
1fx7_A_94	1fx7	A	COCOBALT (II) ION	H - 106
1on2_A_91	1on2	A	MNMANGANESE (II) ION	Y - 95
1on2_A_91	1on2	A	MNMANGANESE (II) ION	V - 98
1on2_A_91	1on2	A	MNMANGANESE (II) ION	E - 99
1on2_A_91	1on2	A	MNMANGANESE (II) ION	E - 102
1on2_A_91	1on2	A	MNMANGANESE (II) ION	H - 103

Clusters included in this Subclass

CLUSTER: HH.4.149

CLUSTER: HH.6.86