ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 4.12.1

Subclass Accession number: 4812
Subclass: 4.12.1

PSSM

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 7

Average sequence ID (%) : 20.4 +/- 24.0
Average RMSD (Å) : 0.614 +/- 0.107

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 90-135

rho (°): 315-360

Consensus Sequence:	XhpGXpXX
(φψ)-conformation:	aapgppaa

Pattern:	x	x	x	x	x	x	x	x	x	[aekqs]	[g]	x	[st]	x	x	[deq]	[ailv]
Conservation:	-0.624	-0.642	-0.960	-0.363	-0.826	-0.407	-0.492	-0.285	0.447	0.103	3.002	-0.609	1.220	-0.518	-0.413	1.192	0.174

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1azo_*_14	1azo	-	16	32	QLLAQAQQLSGYTLGEL	HHHHHHHHTTT-BHHHH	aaaaaaaaaxgxxaaaa
1hb6_A_49	1hb6	A	53	69	AKWDAWNELKGTSKEDA	HHHHHHHHTTT--HHHH	aaaaaaaaapgxxaaaa
1jj2_Q_25	1jj2	Q	27	43	HSKAIAREIKGKTAGEA	HHHHHHHHHTTSBHHHH	aaaaaaaaapvxxaaaa
1lj9_A_92	1lj9	A	105	121	NQHSNQVALQGLSEVEI	HHHHHHHHTTT--HHHH	aaaaaaaaapgxxaaaa
1m9f_C_36	1m9f	C	36	52	VIPMFSALSEGATPQDL	HHHHHHHH-TT--HHHH	aaaaaaaaapvxxaaaa
1m9y_D_36	1m9y	D	36	52	VIPMFSALSEGATPQDL	HHHHHHHHTTT--HHHH	aaaaaaaaaxvxxaaaa
2btm_A_138	2btm	A	142	158	VASQVEKALAGLTPEQV	HHHHHHHHHTT--HHHH	aaaaaaaaapgxbaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	E - 14
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	L - 18
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	A - 21
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	Q - 22
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	Q - 23
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	S - 25
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	G - 26
1azo_*_14	1azo	*	EDO1,2-ETHANEDIOL	Y - 27

Clusters included in this Subclass

CLUSTER: HH.5.129

CLUSTER: HH.6.72