ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 7.22.1

Subclass Accession number: 5025
Subclass: 7.22.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.11 (>50 %)  1.11.1 (>50 %)  1.11.1.5
GO : GO:0004130 (>50 %)  GO:0004601 (>75 %)  GO:0016684 (>75 %)
SCOP : 46625 (>75 %)  46626 (>75 %)  46685 (>75 %)

Number of loops: 3

Average sequence ID (%) : 48.7 +/- 7.5
Average RMSD (Å) : 0.167 +/- 0.058

Consensus geometry

d (Å): 15

delta (°): 90-135

theta (°): 45-90

rho (°): 180-225

Consensus Sequence:	LpGDppALcXp
(φψ)-conformation:	aagpaaabpaa

Pattern:	[KP]	[F]	[D]	[KL]	[WY]	[L]	[EKR]	[G]	[D]	[DKT]	[KNS]	[A]	[L]	[DN]	[AEQ]	[DQS]	[EQ]	[KL]	[EK]	[G]	[LY]	[AKN]	[AL]	[F]	[KM]	[DG]
Conservation:	-0.309	1.469	1.469	-1.045	1.055	0.360	-0.565	1.469	1.469	-1.243	-0.811	0.360	0.360	0.134	-0.996	-0.934	0.114	-1.057	-0.153	1.469	-0.702	-1.304	-0.975	1.469	-0.696	-0.409

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1eb7_A_169	1eb7	A	169	194	PFDLYLKGDDKALDAQQKKGLKAFMD	HHHHHHTT-TTSS-HHHHHHHHHHHH	aaaaaaaNpaaabxaaaaaaaaaaaa
1iqc_A_155	1iqc	A	155	180	KFDKWLEGDKNALNQDELEGYNLFKG	HHHHHHTT-TTSS-HHHHHHHHHHHH	aaaaaaagxaaabxaaaaaaaaaaaa
1nml_A_169	1nml	A	169	194	PFDKYLRGDTSALNESEKEGLALFMD	HHHHHHTT-GGGS-HHHHHHHHHHHH	aaaaaaagxaaabxaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1eb7_A_169	1eb7	A	HECHEME C	A - 191
1eb7_A_169	1eb7	A	HECHEME C	F - 192
1eb7_A_169	1eb7	A	CACALCIUM ION	F - 192
1iqc_A_155	1iqc	A	CACALCIUM ION	F - 178
1iqc_A_155	1iqc	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 178
1iqc_A_155	1iqc	A	CACALCIUM ION	S - 181
1iqc_A_155	1iqc	A	HEMPROTOPORPHYRIN IX CONTAINING FE	S - 181
1nml_A_169	1nml	A	HEMPROTOPORPHYRIN IX CONTAINING FE	F - 192

Clusters included in this Subclass