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Information on SUBCLASS 9.5.2
Subclass Accession number: 5073
Subclass: 9.5.2 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.5 (>50 %)  3.5.1 (>50 %)  3.5.1.88
GO : GO:0008463 (>75 %)  GO:0016810 (>75 %)  GO:0016811 (>75 %)  GO:0042586 (>50 %)  
SCOP : 56419 (>75 %)  56420 (>75 %)  56421 (>75 %)  
 Number of loops: 3

Average sequence ID (%) : 50.0 +/- 8.0
Average RMSD (Å) : 1.167 +/- 0.473

Consensus geometry
d (Å): 21 delta (°): 90-135 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: LXGpLFhDphpXh
(φψ)-conformation: aalbbaaaappaa
Pattern: [G][IL][HL][AS]x[CI][FI][Q][H][E][CFM][D][H][L][NV][G][KT][L][F][IMV][D][KY][LM][ST][PQT][LV][DK][KQR][DKQ][KR][IV][R][KPQ][K][LV][EN][EK]xx[R]
Conservation:1.349-0.215-1.103-0.473-1.388-0.161-0.5300.8252.3970.825-0.9801.3492.3970.301-1.0271.349-0.7230.3011.349-0.4561.349-0.650-0.115-0.373-1.155-0.473-0.622-0.456-0.8640.0510.0430.825-0.9220.825-0.441-0.364-0.207-1.102-1.5630.825
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1g2a_A_1241g2a   A124163GLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRHHHHHHHHHHHHHTTT--GGGGS-HHHHHHHHHHHHHHHHeaaaaaaaaaaaaaavbbaaaabxaaaaaaaaaaaaaaaa
1ix1_A_1261ix1   A126165GLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRHHHHHHHHHHHHHHTT--GGGGS-HHHHHHHHHHHHHHHHeaaaaaaaaaaaaaavbbaaaaxxaaaaaaaaaaaaaaaa
1rl4_A_1901rl4   A190229GIHSRIFQHEFDHLNGTLFIDKMTQVDKKKVRPKLNELIRHHHHHHHHHHHHHHTT--GGGGB-HHHHHHHHHHHHHHHHeaaaaaaaaaaaaaavbbaaaaxpaaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1g2a_A_1241g2a   A     BB2ACTINONIN L - 125
1g2a_A_1241g2a   A     BB2ACTINONIN I - 128
1g2a_A_1241g2a   A     BB2ACTINONIN C - 129
1g2a_A_1241g2a   A     NINICKEL (II) ION H - 132
1g2a_A_1241g2a   A     BB2ACTINONIN H - 132
1g2a_A_1241g2a   A     NINICKEL (II) ION E - 133
1g2a_A_1241g2a   A     BB2ACTINONIN E - 133
1g2a_A_1241g2a   A     NINICKEL (II) ION H - 136
1g2a_A_1241g2a   A     BB2ACTINONIN H - 136
1g2a_A_1241g2a   A     NINICKEL (II) ION L - 141
1g2a_A_1241g2a   A     NINICKEL (II) ION F - 142
1ix1_A_1261ix1   A     BB2ACTINONIN L - 127
1ix1_A_1261ix1   A     MHA(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID L - 128
1ix1_A_1261ix1   A     BB2ACTINONIN V - 130
1ix1_A_1261ix1   A     BB2ACTINONIN C - 131
1ix1_A_1261ix1   A     ZNZINC ION H - 134
1ix1_A_1261ix1   A     BB2ACTINONIN H - 134
1ix1_A_1261ix1   A     ZNZINC ION E - 135
1ix1_A_1261ix1   A     BB2ACTINONIN E - 135
1ix1_A_1261ix1   A     ZNZINC ION H - 138
1ix1_A_1261ix1   A     BB2ACTINONIN H - 138
1ix1_A_1261ix1   A     ZNZINC ION L - 143
1ix1_A_1261ix1   A     ZNZINC ION F - 144
1rl4_A_1901rl4   A     BL52-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE G - 190
1rl4_A_1901rl4   A     BL52-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE I - 191
1rl4_A_1901rl4   A     BRR(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID R - 194
1rl4_A_1901rl4   A     BL52-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE R - 194
1rl4_A_1901rl4   A     BRR(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID I - 195
1rl4_A_1901rl4   A     BL52-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE I - 195
1rl4_A_1901rl4   A     COCOBALT (II) ION H - 198
1rl4_A_1901rl4   A     BRR(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID H - 198
1rl4_A_1901rl4   A     COCOBALT (II) ION E - 199
1rl4_A_1901rl4   A     BRR(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID E - 199
1rl4_A_1901rl4   A     COCOBALT (II) ION H - 202
1rl4_A_1901rl4   A     BRR(2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID H - 202
1rl4_A_1901rl4   A     COCOBALT (II) ION F - 208

Clusters included in this Subclass
CLUSTER: HH.11.51