ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.14.1

Subclass Accession number: 5111
Subclass: 10.14.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.15 (>75 %)  1.15.1 (>75 %)  1.15.1.1
GO : GO:0004784 (>75 %)  GO:0005509 (>75 %)  GO:0005543 (>75 %)  GO:0005544 (>75 %)  GO:0008289 (>75 %)  GO:0016721 (>75 %)
SCOP : 46556 (>75 %)  46609 (>75 %)  46610 (>75 %)  47873 (>75 %)  47874 (>75 %)  47875 (>75 %)  54718 (>75 %)  54719 (>75 %)  54720 (>75 %)

Number of loops: 3

Average sequence ID (%) : 75.0 +/- -33.9
Average RMSD (Å) : 0.467 +/- 0.153

Consensus geometry

d (Å): 25

delta (°): 45-90

theta (°): 135-180

rho (°): 225-270

Consensus Sequence:	LQANRDPDXXhppA
(φψ)-conformation:	aalappppbpppaa

Pattern:	[G]	[HY]	[FY]	[Q]	[R]	[LM]	[L]	[V]	[V]	[L]	[L]	[Q]	[A]	[N]	[R]	[D]	[P]	[D]	[AGT]	[AGR]	[IV]	[DE]	[DE]	[A]	x	[V]	[E]	x	[D]	[A]	[Q]	[AV]	[L]	[F]	[QR]	[A]
Conservation:	1.219	0.373	0.407	0.552	0.552	-0.595	-0.115	-0.115	-0.115	-0.115	-0.115	0.552	-0.115	1.219	0.552	1.219	1.886	1.219	-1.967	-2.116	-0.447	-0.260	-0.305	-0.115	-1.924	-0.115	0.552	-2.190	1.219	-0.115	0.552	-1.445	-0.115	1.219	-0.778	-0.115

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ala_*_147	1ala	-	147	182	GHFQRLLVVLLQANRDPDGRVEEALVEKDAQVLFRA	HHHHHHHHHHHT-----S----HHHHHHHHHHHHHH	eaaaaaaaaaaalaxxxxFxbxaaaaaaaaaaaaaa
1g5n_A_145	1g5n	A	145	180	GYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQA	HHHHHHHHHHHTT---------HHHHHHHHHHHHHH	eaaaaaaaaaaalappxxbpxbaaaaaaaaaaaaaa
1hvd_*_147	1hvd	-	147	182	GYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQA	HHHHHHHHHHHT-----S----HHHHHHHHHHHHHH	eaaaaaaaaaaalaxpxxIxxxaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1g5n_A_145	1g5n	A	CACALCIUM ION	Y - 146
1g5n_A_145	1g5n	A	SGNN,O6-DISULFO-GLUCOSAMINE	P - 161
1g5n_A_145	1g5n	A	SGNN,O6-DISULFO-GLUCOSAMINE	D - 162
1g5n_A_145	1g5n	A	IDU1,4-DIDEOXY-O2-SULFO-GLUCURONIC ACID	D - 162
1g5n_A_145	1g5n	A	SGNN,O6-DISULFO-GLUCOSAMINE	T - 163
1g5n_A_145	1g5n	A	SGNN,O6-DISULFO-GLUCOSAMINE	A - 164
1g5n_A_145	1g5n	A	SGNN,O6-DISULFO-GLUCOSAMINE	I - 165
1g5n_A_145	1g5n	A	CACALCIUM ION	A - 180

Clusters included in this Subclass