Logo
Information on SUBCLASS 2.3.2
Subclass Accession number: 69
Subclass: 2.3.2
Type: HA beta-beta hairpin
DB: ArchDB-KI
Number of loops: 4

Average sequence ID (%) : 20.0 +/- 0.9
Average RMSD (Å) : 0.29 +/- 0.06

Consensus geometry
d (Å): 5 delta (°): 45-90 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: XpGXpp
(φψ)-conformation: bbeabb
Pattern: [ILTV]{DRY}{AWY}[ACFI][CGY]x[EST][G]{DG}[HNY]{NR}{VY}[LM][IV][AIM]
Conservation:-0.027-1.059-0.801-0.543-0.574-0.801-0.0082.592-0.7640.937-0.450-0.5980.9901.118-0.013
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a06_*_811a06   -8195LDDIYESGGHLYLIMEEEEEE-SSEEEEEEbabbbbbeabbbxxx
1bx4_A_1221bx4   A122136TCAACITGDNRSLIAEEEEEEETTEEEEEEbbxbxxbeabbbbbx
1cki_A_711cki   A7185IRWCGAEGDYNVMVMEEEEEEETTEEEEEExabbebbeabxbbbb
2csn_*_712csn   -7185VYYFGQEGLHNVLVIEEEEEEETTEEEEEEbabbbbbeabbbbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bx4_A_1221bx4   A     ADNADENOSINE C - 123
1bx4_A_1221bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED T - 128
1bx4_A_1221bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED D - 130
1bx4_A_1221bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED N - 131
1bx4_A_1221bx4   A     ADNADENOSINE L - 134
1bx4_A_1221bx4   A     ADNADENOSINE A - 136
2csn_*_712csn   *     CKIN-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE I - 85
2csn_*_712csn   *     CKIN-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE D - 86
Bibliographic annotations
LoopPDBChainAnnotationResidue
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AADENINE BINDING RESIDUEC - 123
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998ARIBOSE-ADENOSINEC - 123
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AMg ION BINDING RESIDUE 2D - 130
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AMg ION BINDING RESIDUE 2N - 131
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AADENINE BINDING RESIDUE 1L - 134
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AADENINE-ADENOSINEA - 136
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AADENINE-ADENOSINEA - 136
1bx4_A_1221bx4   RefI.I.MATHEWS,M.D.ERION,S.E.EALICK. STRUCTURE OF HUMAN ADENOSINE KINASE AT 1.5 A RESOLUTION  BIOCHEMISTRY v.37;15607,1998AADENINE BINDING RESIDUE 1A - 136

Clusters included in this Subclass
CLUSTER: HA.1.0
CLUSTER: HA.2.11