ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.8.1

Subclass Accession number: 6926
Subclass: 12.8.1

Type: AR beta-beta link
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 3

Average sequence ID (%) : 69.0 +/- -20.9
Average RMSD (Å) : 0.400 +/- 0.173

Consensus geometry

d (Å): 21

delta (°): 90-135

theta (°): 45-90

rho (°): 270-315

Consensus Sequence:	ISPGDGXTFPKpGpXh
(φψ)-conformation:	abppalapbpbpgpbb

Pattern:	[EKQ]	[IV]	[DE]	[RT]	[I]	[S]	[P]	[G]	[D]	[G]	[AR]	[T]	[F]	[P]	[K]	[KRT]	[G]	[DQ]	[LT]	[CV]	[TV]	[IV]	[H]	[Y]	[T]	[G]	[MT]	[L]
Conservation:	-0.953	-0.450	-0.338	-1.241	-0.195	-0.195	1.380	0.855	0.855	0.855	-1.359	0.330	0.855	1.380	0.330	-1.420	0.855	-0.861	-1.359	-0.777	-1.124	-0.457	1.905	1.380	0.330	0.855	-1.241	-0.195

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1c9h_A_2	1c9h	A	3	30	EIETISPGDGRTFPKKGQTCVVHYTGML	EEEEEE---SS----TT-EEEEEEEEEE	bbbxabxxavNxbxxpgxbxbbbbbbbx
1fkl_*_2	1fkl	-	3	30	QVETISPGDGRTFPKRGQTCVVHYTGML	EEEEEE---SS----TT-EEEEEEEEEE	bbbxabxxavaxbxbxgxxxbbbbbbbx
1yat_*_3	1yat	-	3	30	KIDRISPGDGATFPKTGDLVTIHYTGTL	EEEEEE---SS----TT-EEEEEEEEEE	bbbxabxbaUaxbxbpgxxbbbbbbbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1c9h_A_2	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	Y - 26
1c9h_A_2	1c9h	A	RAPRAPAMYCIN IMMUNOSUPPRESSANT DRUG	G - 28
1yat_*_3	1yat	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	Y - 26
1yat_*_3	1yat	*	FK58-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	G - 28

Clusters included in this Subclass