Logo
Information on SUBCLASS 4.2.3
Subclass Accession number: 9039
Subclass: 4.2.3 PSSM
Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 3

Average sequence ID (%) : 9.7 +/- 11.0
Average RMSD (Å) : 1.000 +/- 0.300

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: ppcpXpXh
(φψ)-conformation: aalappaa
Pattern: x[AEG][ENW][IW]xx[FTV]x[HN][EGR][GIL][DER][DQT][GN][ET][HI][ST][AEP][GV]xx[AI][AGV][LV]xx[GST][AFI]x[FIL]x
Conservation:-1.014-0.393-0.5180.356-0.766-0.890-0.393-0.3932.956-0.518-1.2630.476-0.0212.2071.089-0.0481.574-0.2690.366-0.890-1.1380.426-0.5181.465-0.269-0.3930.103-0.518-1.1380.724-0.393
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1e2k_A_961e2k   A97127IANIYTTQHRLDQGEISAGDAAVVMTSAQITHHHHHHHHHHHHHTSS-HHHHHHHHHHHHHHaaaaaaaaaaaaavabxaaaaaaaaaaaaaa
1qle_C_531qle   C6393FGWWADVVNEGETGEHTPVVRIGLQYGFILFHHHHHHHHHHHHTT---HHHHHHHHHHHHHHaaaaaaaaaaaaavaxpaaaaaaaaaaaaaa
2tpt_*_192tpt   -1949DEEIRFFINGIRDNTISEGQIAALAMTIFFHHHHHHHHHHHHHHT-S-HHHHHHHHHHHHHHaaaaaaaaaaaaavaxxaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE I - 97
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE I - 100
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE Y - 101
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE Q - 125
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE M - 128
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE G - 129
1e2k_A_961e2k   A     TMC1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE Y - 132
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE L - 55
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE V - 58
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE L - 59
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE M - 62
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE W - 65
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE W - 66
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE A - 67
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE V - 69
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE V - 70
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE G - 73
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE E - 74
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE G - 76
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE H - 78
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE V - 82
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE L - 86
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE F - 90
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE F - 93
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE M - 99
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE V - 102
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE W - 106
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE K - 110
1qle_C_531qle   C     PC2DI-STEAROYL-3-SN-PHOSPHATIDYLCHOLINE L - 113
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1e2k_A_961e2k   A AC1TMC BINDING SITE FOR CHAIN AI - 97
1e2k_A_961e2k   A AC1TMC BINDING SITE FOR CHAIN AI - 100
1e2k_A_961e2k   A AC1TMC BINDING SITE FOR CHAIN AY - 101
1e2k_A_961e2k   A AC1TMC BINDING SITE FOR CHAIN AQ - 125
1e2k_A_961e2k   A AC1TMC BINDING SITE FOR CHAIN AM - 128

Clusters included in this Subclass
CLUSTER: HH.4.160