PDB: 1a12 Compound: regulator of chromosome condensation 1 Classification: GUANINE NUCLEOTIDE EXCHANGE FACTOR Entry date in PDB: 1999-01-13 Resolution [Å]: 1.70 R-Factor: 0.189

CHAIN: A SWISS-PROT/TREMBL: P18754    KEYWORD: 3D-structure    Cell cycle    DNA-binding    Guanine-nucleotide releasing factor    Mitosis    Nuclear protein    Repeat    SCOP: b.69.5.1 All beta proteins    7-bladed beta-propeller    RCC1/BLIP-II    Regulator of chromosome condensation RCC1    Regulator of chromosome condensation RCC1    Human (Homo sapiens) GO:   CHAIN: B SWISS-PROT/TREMBL: P18754    KEYWORD: 3D-structure    Cell cycle    DNA-binding    Guanine-nucleotide releasing factor    Mitosis    Nuclear protein    Repeat    SCOP: b.69.5.1 All beta proteins    7-bladed beta-propeller    RCC1/BLIP-II    Regulator of chromosome condensation RCC1    Regulator of chromosome condensation RCC1    Human (Homo sapiens) GO:   CHAIN: C SWISS-PROT/TREMBL: P18754    KEYWORD: 3D-structure    Cell cycle    DNA-binding    Guanine-nucleotide releasing factor    Mitosis    Nuclear protein    Repeat    SCOP: b.69.5.1 All beta proteins    7-bladed beta-propeller    RCC1/BLIP-II    Regulator of chromosome condensation RCC1    Regulator of chromosome condensation RCC1    Human (Homo sapiens) GO:

Image Source: PDB

Loops in ArchDB40 clusters

1a12_A_146 - HA => SUBCLASS : 2.2.2
1a12_A_174 - HA => SUBCLASS : 2.2.3
1a12_A_121 - HA => SUBCLASS : 2.2.3
1a12_A_347 - HA => SUBCLASS : 2.2.3
1a12_A_69 - HA => SUBCLASS : 2.2.3
1a12_A_296 - HA => SUBCLASS : 2.2.3
1a12_A_399 - HA => SUBCLASS : 2.2.3
1a12_A_183 - HA => SUBCLASS : 4.2.1
1a12_A_251 - HA => SUBCLASS : 4.2.1
1a12_A_130 - HA => SUBCLASS : 4.2.1
1a12_A_356 - HA => SUBCLASS : 4.2.1
1a12_A_78 - HA => SUBCLASS : 4.2.1
1a12_A_305 - HA => SUBCLASS : 4.2.1
1a12_A_113 - AR => SUBCLASS : 2.1.2
1a12_A_113 - AR => SUBCLASS : 3.10.1
1a12_A_162 - AR => SUBCLASS : 3.16.2
1a12_A_335 - AR => SUBCLASS : 6.6.2
1a12_A_335 - AR => SUBCLASS : 6.12.1

Loops in ArchDB95 clusters

1a12_A_113 - AR => SUBCLASS : 5.18.1
1a12_A_335 - AR => SUBCLASS : 6.21.1
1a12_A_146 - HA => SUBCLASS : 2.2.2
1a12_A_121 - HA => SUBCLASS : 2.2.3
1a12_A_399 - HA => SUBCLASS : 2.2.3
1a12_A_296 - HA => SUBCLASS : 2.2.3
1a12_A_69 - HA => SUBCLASS : 2.2.3
1a12_A_174 - HA => SUBCLASS : 2.2.3
1a12_A_347 - HA => SUBCLASS : 2.2.3
1a12_A_183 - HA => SUBCLASS : 3.1.2
1a12_A_356 - HA => SUBCLASS : 3.1.2
1a12_A_251 - HA => SUBCLASS : 3.1.2
1a12_A_130 - HA => SUBCLASS : 3.1.2
1a12_A_305 - HA => SUBCLASS : 3.1.2
1a12_A_78 - HA => SUBCLASS : 3.1.2

Loops not clustered in ArchDB

1a12_A_56 - AR
1a12_A_140 - AR
1a12_A_151 - AR
1a12_A_227 - AR
1a12_A_385 - AR
1a12_A_280 - AR
1a12_A_193 - EH
1a12_A_36 - HA
1a12_A_366 - HA
1a12_A_315 - HA
1a12_A_261 - HA
1a12_A_242 - HA
1a12_A_88 - HA
1a12_A_220 - HE

1a12 A - percentage of sequence identity: 100
1a12 B - percentage of sequence identity: 100
1a12 C - percentage of sequence identity: 100
1i2m B - percentage of sequence identity: 100
1i2m D - percentage of sequence identity: 100