PDB: 1afs Compound: 3-alpha-hydroxysteroid dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 1997-10-08 Resolution [Å]: 2.50 R-Factor: 0.188

CHAIN: A SWISS-PROT/TREMBL: P23457    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.50 SCOP: c.1.7.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    NAD(P)-linked oxidoreductase    Aldo-keto reductases (NADP)    3-alpha-hydroxysteroid dehydrogenase    Rat (Rattus norvegicus) GO:  oxidoreductase activity    CHAIN: B SWISS-PROT/TREMBL: P23457    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.50 SCOP: c.1.7.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    NAD(P)-linked oxidoreductase    Aldo-keto reductases (NADP)    3-alpha-hydroxysteroid dehydrogenase    Rat (Rattus norvegicus) GO:  oxidoreductase activity

Image Source: PDB

Loops in ArchDB95 clusters

1afs_A_139 - EH => SUBCLASS : 3.4.3
1afs_A_160 - EH => SUBCLASS : 3.6.4
1afs_A_266 - EH => SUBCLASS : 4.3.1
1afs_A_48 - EH => SUBCLASS : 4.20.1
1afs_A_188 - EH => SUBCLASS : 5.22.1
1afs_A_80 - EH => SUBCLASS : 6.6.3
1afs_A_15 - AR => SUBCLASS : 1.2.2
1afs_A_15 - AR => SUBCLASS : 1.2.12
1afs_A_111 - AR => SUBCLASS : 1.2.16
1afs_A_239 - HH => SUBCLASS : 3.1.1
1afs_A_274 - HH => SUBCLASS : 4.17.3
1afs_A_7 - HA => SUBCLASS : 3.1.1

Loops in ArchDB-EC clusters

1afs_A_239 - HH => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

1afs_A_111 - AR
1afs_A_15 - AR
1afs_A_20 - EH
1afs_A_212 - EH
1afs_A_7 - HA
1afs_A_121 - HA
1afs_A_121 - HA
1afs_A_170 - HE
1afs_A_252 - HE
1afs_A_144 - HE
1afs_A_95 - HE
1afs_A_58 - HE
1afs_A_33 - HE
1afs_A_200 - HE

1afs A - percentage of sequence identity: 100
1afs B - percentage of sequence identity: 100
1ihi A - percentage of sequence identity: 68
1ihi B - percentage of sequence identity: 68
1j96 A - percentage of sequence identity: 69
1j96 B - percentage of sequence identity: 69
1lwi A - percentage of sequence identity: 100
1lwi B - percentage of sequence identity: 100
1mrq A - percentage of sequence identity: 69
1q13 A - percentage of sequence identity: 72
1q13 B - percentage of sequence identity: 72
1q5m A - percentage of sequence identity: 73
1q5m B - percentage of sequence identity: 73
1ral - - percentage of sequence identity: 100
1ry0 A - percentage of sequence identity: 69
1ry0 B - percentage of sequence identity: 69
1ry8 A - percentage of sequence identity: 69
1ry8 B - percentage of sequence identity: 69
1s1p A - percentage of sequence identity: 69
1s1r A - percentage of sequence identity: 69
1s2a A - percentage of sequence identity: 69
1s2c A - percentage of sequence identity: 69
1xf0 A - percentage of sequence identity: 69
1xjb A - percentage of sequence identity: 69
1xjb B - percentage of sequence identity: 69
2fvl A - percentage of sequence identity: 68
2fvl B - percentage of sequence identity: 68
2fvl C - percentage of sequence identity: 68