PDB: 1amu Compound: gramicidin synthetase 1 Classification: PEPTIDE SYNTHETASE Entry date in PDB: 1998-07-01 Resolution [Å]: 1.90 R-Factor: 0.213

CHAIN: A SWISS-PROT/TREMBL: P14687    KEYWORD: 3D-structure    Antibiotic biosynthesis    Isomerase    Ligase    Multifunctional enzyme    Phosphopantetheine    EC: 5.1.1.11 SCOP: e.23.1.1 Multi-domain proteins (alpha and beta)    Acetyl-CoA synthetase-like    Acetyl-CoA synthetase-like    Acetyl-CoA synthetase-like    Phenylalanine activating domain of gramicidin synthetase 1    Bacillus brevis GO:  catalytic activity    cofactor binding    ligase activity    molecular function unknown    phosphopantetheine binding    metabolism    CHAIN: B SWISS-PROT/TREMBL: P14687    KEYWORD: 3D-structure    Antibiotic biosynthesis    Isomerase    Ligase    Multifunctional enzyme    Phosphopantetheine    EC: 5.1.1.11 SCOP: e.23.1.1 Multi-domain proteins (alpha and beta)    Acetyl-CoA synthetase-like    Acetyl-CoA synthetase-like    Acetyl-CoA synthetase-like    Phenylalanine activating domain of gramicidin synthetase 1    Bacillus brevis GO:  catalytic activity    cofactor binding    ligase activity    molecular function unknown    phosphopantetheine binding    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1amu_A_432 - HA => SUBCLASS : 2.1.1
1amu_A_56 - HA => SUBCLASS : 2.3.1
1amu_A_455 - HA => SUBCLASS : 4.2.2
1amu_A_407 - HA => SUBCLASS : 5.1.4
1amu_A_396 - HA => SUBCLASS : 6.5.1
1amu_A_198 - EH => SUBCLASS : 0.1.6
1amu_A_198 - EH => SUBCLASS : 0.1.11
1amu_A_250 - EH => SUBCLASS : 1.1.5
1amu_A_139 - EH => SUBCLASS : 1.1.7
1amu_A_139 - EH => SUBCLASS : 1.1.10
1amu_A_385 - EH => SUBCLASS : 2.9.1
1amu_A_115 - EH => SUBCLASS : 5.1.4
1amu_A_225 - EH => SUBCLASS : 6.36.1
1amu_A_350 - AR => SUBCLASS : 3.5.1
1amu_A_350 - AR => SUBCLASS : 3.5.2
1amu_A_423 - AR => SUBCLASS : 4.2.1

Loops in ArchDB95 clusters

1amu_A_198 - EH => SUBCLASS : 0.1.5
1amu_A_198 - EH => SUBCLASS : 0.1.33
1amu_A_198 - EH => SUBCLASS : 0.1.49
1amu_A_250 - EH => SUBCLASS : 1.1.3
1amu_A_139 - EH => SUBCLASS : 1.1.53
1amu_A_139 - EH => SUBCLASS : 1.2.2
1amu_A_91 - EH => SUBCLASS : 3.8.5
1amu_A_91 - EH => SUBCLASS : 3.8.7
1amu_A_385 - EH => SUBCLASS : 3.19.2
1amu_A_115 - EH => SUBCLASS : 5.1.7
1amu_A_470 - EH => SUBCLASS : 5.10.1
1amu_A_297 - EH => SUBCLASS : 5.50.1
1amu_A_225 - EH => SUBCLASS : 6.61.1
1amu_A_350 - AR => SUBCLASS : 1.1.1
1amu_A_350 - AR => SUBCLASS : 1.1.2
1amu_A_423 - AR => SUBCLASS : 3.2.3
1amu_A_423 - AR => SUBCLASS : 4.4.1
1amu_A_432 - HA => SUBCLASS : 2.1.1
1amu_A_56 - HA => SUBCLASS : 2.3.1
1amu_A_455 - HA => SUBCLASS : 5.1.4
1amu_A_407 - HA => SUBCLASS : 5.4.2
1amu_A_407 - HA => SUBCLASS : 5.4.4
1amu_A_396 - HA => SUBCLASS : 7.1.1

Loops in ArchDB-EC clusters

1amu_A_67 - HE => SUBCLASS : 6.31.1

Loops not clustered in ArchDB

1amu_A_350 - AR
1amu_A_158 - AR
1amu_A_372 - AR
1amu_A_158 - AR
1amu_A_423 - AR
1amu_A_372 - AR
1amu_A_63 - EH
1amu_A_276 - EH
1amu_A_438 - EH
1amu_A_396 - HA
1amu_A_355 - HA
1amu_A_56 - HA
1amu_A_432 - HA
1amu_A_184 - HA
1amu_A_318 - HA
1amu_A_333 - HA
1amu_A_407 - HA
1amu_A_355 - HA
1amu_A_333 - HA
1amu_A_318 - HA
1amu_A_184 - HA
1amu_A_455 - HA
1amu_A_262 - HE
1amu_A_41 - HE
1amu_A_100 - HE
1amu_A_125 - HE
1amu_A_147 - HE
1amu_A_205 - HE
1amu_A_236 - HE
1amu_A_281 - HE
1amu_A_307 - HE
1amu_A_390 - HE
1amu_A_442 - HE
1amu_A_484 - HE
1amu_A_256 - HH
1amu_A_20 - HH

1amu A - percentage of sequence identity: 100
1amu B - percentage of sequence identity: 100