PDB: 1b43 Compound: fen-1 Classification: TRANSFERASE Entry date in PDB: 2000-01-12 Resolution [Å]: 2.00 R-Factor: 0.231

CHAIN: A SWISS-PROT/TREMBL: O93634    KEYWORD: 3D-structure    Complete proteome    Endonuclease    Hydrolase    Magnesium    Metal-binding    Nuclease    EC: 3.-.-.- SCOP: a.60.7.1 All alpha proteins    SAM domain-like    5' to 3' exonuclease, C-terminal subdomain    5' to 3' exonuclease, C-terminal subdomain    Flap endonuclease-1 (Fen-1 nuclease)    Archaeon Pyrococcus furiosus SCOP: c.120.1.2 Alpha and beta proteins (a/b)    PIN domain-like    PIN domain-like    5' to 3' exonuclease catalytic domain    Flap endonuclease-1 (Fen-1 nuclease)    Archaeon Pyrococcus furiosus GO:  DNA binding    nuclease activity    DNA repair    CHAIN: B SWISS-PROT/TREMBL: O93634    KEYWORD: 3D-structure    Complete proteome    Endonuclease    Hydrolase    Magnesium    Metal-binding    Nuclease    EC: 3.-.-.- SCOP: a.60.7.1 All alpha proteins    SAM domain-like    5' to 3' exonuclease, C-terminal subdomain    5' to 3' exonuclease, C-terminal subdomain    Flap endonuclease-1 (Fen-1 nuclease)    Archaeon Pyrococcus furiosus SCOP: c.120.1.2 Alpha and beta proteins (a/b)    PIN domain-like    PIN domain-like    5' to 3' exonuclease catalytic domain    Flap endonuclease-1 (Fen-1 nuclease)    Archaeon Pyrococcus furiosus GO:  DNA binding    nuclease activity    DNA repair

Image Source: PDB

Loops in ArchDB95 clusters

1b43_A_167 - EH => SUBCLASS : 2.3.9
1b43_A_145 - EH => SUBCLASS : 3.4.1
1b43_A_11 - AR => SUBCLASS : 8.29.1
1b43_A_296 - HH => SUBCLASS : 3.1.13
1b43_A_211 - HH => SUBCLASS : 3.4.1
1b43_A_27 - HH => SUBCLASS : 16.7.1
1b43_A_55 - HE => SUBCLASS : 1.1.1
1b43_A_128 - HE => SUBCLASS : 2.1.1
1b43_A_174 - HE => SUBCLASS : 3.1.3
1b43_A_152 - HE => SUBCLASS : 4.4.3

Loops in ArchDB-EC clusters

1b43_A_296 - HH => SUBCLASS : 3.3.12

Loops not clustered in ArchDB

1b43_A_201 - AR
1b43_A_182 - AR
1b43_A_11 - AR
1b43_A_201 - AR
1b43_A_182 - AR
1b43_A_22 - EH
1b43_A_207 - EH
1b43_A_73 - EH
1b43_A_191 - HA
1b43_A_191 - HA
1b43_A_246 - HH
1b43_A_222 - HH
1b43_A_113 - HH
1b43_A_99 - HH
1b43_A_271 - HH

1b43 A - percentage of sequence identity: 100
1b43 B - percentage of sequence identity: 100
1mc8 A - percentage of sequence identity: 88
1mc8 B - percentage of sequence identity: 88
1rxv A - percentage of sequence identity: 61
1rxv B - percentage of sequence identity: 61
1rxw A - percentage of sequence identity: 61