PDB: 1bzy Compound: hypoxanthine-guanine phosphoribosyltransferase Classification: PHOSPHORIBOSYLTRANSFERASE Entry date in PDB: 1999-06-22 Resolution [Å]: 2.00 R-Factor: 0.190

CHAIN: A SWISS-PROT/TREMBL: P00492    KEYWORD: 3D-structure    Acetylation    Disease mutation    Glycosyltransferase    Gout    Magnesium    Metal-binding    Purine salvage    Transferase    EC: 2.4.2.8 SCOP: c.61.1.1 Alpha and beta proteins (a/b)    PRTase-like    PRTase-like    Phosphoribosyltransferases (PRTases)    Hypoxanthine-guanine PRTase (HGPRTase)    Human (Homo sapiens) GO:  cytoplasm    hypoxanthine phosphoribosyltransferase activity    transferase activity    nucleoside metabolism    purine ribonucleoside salvage    CHAIN: B SWISS-PROT/TREMBL: P00492    KEYWORD: 3D-structure    Acetylation    Disease mutation    Glycosyltransferase    Gout    Magnesium    Metal-binding    Purine salvage    Transferase    EC: 2.4.2.8 SCOP: c.61.1.1 Alpha and beta proteins (a/b)    PRTase-like    PRTase-like    Phosphoribosyltransferases (PRTases)    Hypoxanthine-guanine PRTase (HGPRTase)    Human (Homo sapiens) GO:  cytoplasm    hypoxanthine phosphoribosyltransferase activity    transferase activity    nucleoside metabolism    purine ribonucleoside salvage    CHAIN: C SWISS-PROT/TREMBL: P00492    KEYWORD: 3D-structure    Acetylation    Disease mutation    Glycosyltransferase    Gout    Magnesium    Metal-binding    Purine salvage    Transferase    EC: 2.4.2.8 SCOP: c.61.1.1 Alpha and beta proteins (a/b)    PRTase-like    PRTase-like    Phosphoribosyltransferases (PRTases)    Hypoxanthine-guanine PRTase (HGPRTase)    Human (Homo sapiens) GO:  cytoplasm    hypoxanthine phosphoribosyltransferase activity    transferase activity    nucleoside metabolism    purine ribonucleoside salvage    CHAIN: D SWISS-PROT/TREMBL: P00492    KEYWORD: 3D-structure    Acetylation    Disease mutation    Glycosyltransferase    Gout    Magnesium    Metal-binding    Purine salvage    Transferase    EC: 2.4.2.8 SCOP: c.61.1.1 Alpha and beta proteins (a/b)    PRTase-like    PRTase-like    Phosphoribosyltransferases (PRTases)    Hypoxanthine-guanine PRTase (HGPRTase)    Human (Homo sapiens) GO:  cytoplasm    hypoxanthine phosphoribosyltransferase activity    transferase activity    nucleoside metabolism    purine ribonucleoside salvage

Image Source: PDB

Loops in ArchDB40 clusters

1bzy_A_140 - HE => SUBCLASS : 3.1.1
1bzy_A_187 - HA => SUBCLASS : 14.1.1
1bzy_A_61 - EH => SUBCLASS : 2.8.1

Loops in ArchDB95 clusters

1bzy_A_61 - EH => SUBCLASS : 2.8.1
1bzy_A_38 - HE => SUBCLASS : 2.6.14
1bzy_A_140 - HE => SUBCLASS : 3.1.1
1bzy_A_140 - HE => SUBCLASS : 3.3.2
1bzy_A_187 - HA => SUBCLASS : 14.2.1

Loops in ArchDB-EC clusters

1bzy_A_140 - HE => SUBCLASS : 3.1.1

Loops not clustered in ArchDB

1bzy_A_7 - AR
1bzy_A_177 - AR
1bzy_A_108 - AR
1bzy_A_177 - AR
1bzy_A_7 - AR
1bzy_A_108 - AR
1bzy_A_31 - EH
1bzy_A_204 - EH
1bzy_A_128 - EH
1bzy_A_156 - HA
1bzy_A_94 - HA
1bzy_A_156 - HA
1bzy_A_94 - HA
1bzy_A_187 - HA
1bzy_A_71 - HE

1bzy A - percentage of sequence identity: 100
1bzy B - percentage of sequence identity: 100
1bzy C - percentage of sequence identity: 100
1bzy D - percentage of sequence identity: 100
1d6n A - percentage of sequence identity: 99
1d6n B - percentage of sequence identity: 99
1hmp A - percentage of sequence identity: 100
1hmp B - percentage of sequence identity: 100
1z7g A - percentage of sequence identity: 100
1z7g B - percentage of sequence identity: 100
1z7g C - percentage of sequence identity: 100
1z7g D - percentage of sequence identity: 100