PDB: 1c0m Compound: integrase Classification: TRANSFERASE Entry date in PDB: 2000-03-01 Resolution [Å]: 2.53 R-Factor: 0.216

CHAIN: A SWISS-PROT/TREMBL: P03354    KEYWORD: 3D-structure    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.34.7.1 All beta proteins    SH3-like barrel    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    Rous sarcoma virus (RSV, avian sarcoma virus) SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Rous sarcoma virus (RSV, avian sarcoma virus) GO:  DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    RNA-dependent DNA replication    CHAIN: B SWISS-PROT/TREMBL: P03354    KEYWORD: 3D-structure    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.34.7.1 All beta proteins    SH3-like barrel    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    Rous sarcoma virus (RSV, avian sarcoma virus) SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Rous sarcoma virus (RSV, avian sarcoma virus) GO:  DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    RNA-dependent DNA replication    CHAIN: C SWISS-PROT/TREMBL: P03354    KEYWORD: 3D-structure    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.34.7.1 All beta proteins    SH3-like barrel    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    Rous sarcoma virus (RSV, avian sarcoma virus) SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Rous sarcoma virus (RSV, avian sarcoma virus) GO:  DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    RNA-dependent DNA replication    CHAIN: D SWISS-PROT/TREMBL: P03354    KEYWORD: 3D-structure    Endonuclease    Hydrolase    Metal-binding    Nuclease    Polyprotein    RNA-directed DNA polymerase    Transferase    Zinc    Zinc-finger    EC: 2.7.7.49 SCOP: b.34.7.1 All beta proteins    SH3-like barrel    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    DNA-binding domain of retroviral integrase    Rous sarcoma virus (RSV, avian sarcoma virus) SCOP: c.55.3.2 Alpha and beta proteins (a/b)    Ribonuclease H-like motif    Ribonuclease H-like    Retroviral integrase, catalytic domain    Retroviral integrase, catalytic domain    Rous sarcoma virus (RSV, avian sarcoma virus) GO:  DNA binding    integrase activity    nucleic acid binding    ribonuclease H activity    RNA binding    RNA-directed DNA polymerase activity    zinc ion binding    DNA integration    DNA recombination    RNA-dependent DNA replication

Image Source: PDB

1cxq A - percentage of sequence identity: 98