PDB: 1c30 Compound: carbamoyl phosphate synthetase Classification: LIGASE Entry date in PDB: 1999-12-10 Resolution [Å]: 2.00 R-Factor: 0.189

CHAIN: A SWISS-PROT/TREMBL: P00968    KEYWORD: 3D-structure    Arginine biosynthesis    ATP-binding    Complete proteome    Ligase    Manganese    Pyrimidine biosynthesis    Repeat    EC: 6.3.5.5 SCOP: a.92.1.1 All alpha proteins    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Escherichia coli SCOP: c.24.1.1 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli GO:  cytoplasm    ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    ligase activity    arginine biosynthesis    metabolism    nitrogen compound metabolism    pyrimidine base biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P00907    KEYWORD: 3D-structure    Arginine biosynthesis    Complete proteome    Glutamine amidotransferase    Ligase    Pyrimidine biosynthesis    EC: 6.3.5.5 SCOP: c.8.3.1 Alpha and beta proteins (a/b)    The "swivelling" beta/beta/alpha domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Escherichia coli SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    Carbamoyl phosphate synthetase, small subunit C-terminal domain    Escherichia coli GO:  ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    biosynthesis    glutamine metabolism    nitrogen compound metabolism    CHAIN: C SWISS-PROT/TREMBL: P00968    KEYWORD: 3D-structure    Arginine biosynthesis    ATP-binding    Complete proteome    Ligase    Manganese    Pyrimidine biosynthesis    Repeat    EC: 6.3.5.5 SCOP: a.92.1.1 All alpha proteins    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Escherichia coli SCOP: c.24.1.1 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli GO:  cytoplasm    ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    ligase activity    arginine biosynthesis    metabolism    nitrogen compound metabolism    pyrimidine base biosynthesis    CHAIN: D SWISS-PROT/TREMBL: P00907    KEYWORD: 3D-structure    Arginine biosynthesis    Complete proteome    Glutamine amidotransferase    Ligase    Pyrimidine biosynthesis    EC: 6.3.5.5 SCOP: c.8.3.1 Alpha and beta proteins (a/b)    The "swivelling" beta/beta/alpha domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Escherichia coli SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    Carbamoyl phosphate synthetase, small subunit C-terminal domain    Escherichia coli GO:  ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    biosynthesis    glutamine metabolism    nitrogen compound metabolism    CHAIN: E SWISS-PROT/TREMBL: P00968    KEYWORD: 3D-structure    Arginine biosynthesis    ATP-binding    Complete proteome    Ligase    Manganese    Pyrimidine biosynthesis    Repeat    EC: 6.3.5.5 SCOP: a.92.1.1 All alpha proteins    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Escherichia coli SCOP: c.24.1.1 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli GO:  cytoplasm    ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    ligase activity    arginine biosynthesis    metabolism    nitrogen compound metabolism    pyrimidine base biosynthesis    CHAIN: F SWISS-PROT/TREMBL: P00907    KEYWORD: 3D-structure    Arginine biosynthesis    Complete proteome    Glutamine amidotransferase    Ligase    Pyrimidine biosynthesis    EC: 6.3.5.5 SCOP: c.8.3.1 Alpha and beta proteins (a/b)    The "swivelling" beta/beta/alpha domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Escherichia coli SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    Carbamoyl phosphate synthetase, small subunit C-terminal domain    Escherichia coli GO:  ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    biosynthesis    glutamine metabolism    nitrogen compound metabolism    CHAIN: G SWISS-PROT/TREMBL: P00968    KEYWORD: 3D-structure    Arginine biosynthesis    ATP-binding    Complete proteome    Ligase    Manganese    Pyrimidine biosynthesis    Repeat    EC: 6.3.5.5 SCOP: a.92.1.1 All alpha proteins    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Carbamoyl phosphate synthetase, large subunit connection domain    Escherichia coli SCOP: c.24.1.1 Alpha and beta proteins (a/b)    Methylglyoxal synthase-like    Methylglyoxal synthase-like    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: c.30.1.1 Alpha and beta proteins (a/b)    PreATP-grasp domain    PreATP-grasp domain    BC N-terminal domain-like    Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli SCOP: d.142.1.2 Alpha and beta proteins (a+b)    ATP-grasp    Glutathione synthetase ATP-binding domain-like    BC ATP-binding domain-like    Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains    Escherichia coli GO:  cytoplasm    ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    ligase activity    arginine biosynthesis    metabolism    nitrogen compound metabolism    pyrimidine base biosynthesis    CHAIN: H SWISS-PROT/TREMBL: P00907    KEYWORD: 3D-structure    Arginine biosynthesis    Complete proteome    Glutamine amidotransferase    Ligase    Pyrimidine biosynthesis    EC: 6.3.5.5 SCOP: c.8.3.1 Alpha and beta proteins (a/b)    The "swivelling" beta/beta/alpha domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Carbamoyl phosphate synthetase, small subunit N-terminal domain    Escherichia coli SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    Carbamoyl phosphate synthetase, small subunit C-terminal domain    Escherichia coli GO:  ATP binding    carbamoyl-phosphate synthase activity    catalytic activity    biosynthesis    glutamine metabolism    nitrogen compound metabolism

Image Source: PDB

Loops in ArchDB-EC clusters

1c30_A_420 - HH => SUBCLASS : 3.16.1

Loops not clustered in ArchDB

1c30_A_204 - AR
1c30_A_542 - AR
1c30_A_712 - AR
1c30_A_9 - EH
1c30_A_836 - EH
1c30_A_915 - EH
1c30_A_944 - EH
1c30_A_970 - EH
1c30_A_989 - EH
1c30_A_1012 - EH
1c30_A_1039 - EH
1c30_A_794 - EH
1c30_A_727 - EH
1c30_A_637 - EH
1c30_A_63 - EH
1c30_A_85 - EH
1c30_A_114 - EH
1c30_A_146 - EH
1c30_A_180 - EH
1c30_A_249 - EH
1c30_A_295 - EH
1c30_A_615 - EH
1c30_A_382 - EH
1c30_A_561 - EH
1c30_A_43 - HA
1c30_A_166 - HA
1c30_A_214 - HA
1c30_A_228 - HA
1c30_A_280 - HA
1c30_A_525 - HA
1c30_A_595 - HA
1c30_A_760 - HA
1c30_A_773 - HA
1c30_A_824 - HA
1c30_A_888 - HA
1c30_A_355 - HA
1c30_A_924 - HE
1c30_A_258 - HE
1c30_A_874 - HE
1c30_A_319 - HE
1c30_A_510 - HE
1c30_A_576 - HE
1c30_A_623 - HE
1c30_A_698 - HE
1c30_A_803 - HE
1c30_A_185 - HE
1c30_A_152 - HE
1c30_A_954 - HE
1c30_A_975 - HE
1c30_A_1001 - HE
1c30_A_1020 - HE
1c30_A_25 - HE
1c30_A_71 - HE
1c30_A_107 - HE
1c30_A_129 - HE
1c30_A_731 - HE
1c30_A_1044 - HH
1c30_A_92 - HH
1c30_A_120 - HH
1c30_A_306 - HH
1c30_A_391 - HH
1c30_A_435 - HH
1c30_A_449 - HH
1c30_A_460 - HH
1c30_A_486 - HH
1c30_A_499 - HH
1c30_A_645 - HH
1c30_A_666 - HH
1c30_A_675 - HH
1c30_A_850 - HH
1c30_A_861 - HH

1a9x A - percentage of sequence identity: 99
1a9x C - percentage of sequence identity: 99
1a9x E - percentage of sequence identity: 99
1a9x G - percentage of sequence identity: 99
1bxr A - percentage of sequence identity: 100
1bxr C - percentage of sequence identity: 100
1bxr E - percentage of sequence identity: 100
1bxr G - percentage of sequence identity: 100
1c30 A - percentage of sequence identity: 100
1c30 C - percentage of sequence identity: 100
1c30 E - percentage of sequence identity: 100
1c30 G - percentage of sequence identity: 100
1c3o A - percentage of sequence identity: 100
1c3o C - percentage of sequence identity: 100
1c3o E - percentage of sequence identity: 100
1c3o G - percentage of sequence identity: 100
1ce8 A - percentage of sequence identity: 99
1ce8 C - percentage of sequence identity: 99
1ce8 E - percentage of sequence identity: 99
1ce8 G - percentage of sequence identity: 99
1cs0 A - percentage of sequence identity: 100
1cs0 C - percentage of sequence identity: 100
1cs0 E - percentage of sequence identity: 100
1cs0 G - percentage of sequence identity: 100
1jdb B - percentage of sequence identity: 100
1jdb E - percentage of sequence identity: 100
1jdb H - percentage of sequence identity: 100
1jdb K - percentage of sequence identity: 100
1kee A - percentage of sequence identity: 100
1kee C - percentage of sequence identity: 100
1kee E - percentage of sequence identity: 100
1kee G - percentage of sequence identity: 100
1m6v A - percentage of sequence identity: 99
1m6v C - percentage of sequence identity: 99
1m6v E - percentage of sequence identity: 99
1m6v G - percentage of sequence identity: 99
1t36 A - percentage of sequence identity: 100
1t36 C - percentage of sequence identity: 100
1t36 E - percentage of sequence identity: 100
1t36 G - percentage of sequence identity: 100
null nu - percentage of sequence identity: 0