PDB: 1e0t Compound: pyruvate kinase Classification: PHOSPHOTRANSFERASE Entry date in PDB: 2000-04-11 Resolution [Å]: 1.80 R-Factor: 0.246

CHAIN: A SWISS-PROT/TREMBL: P14178    KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Glycolysis    Kinase    Magnesium    Multigene family    Transferase    EC: 2.7.1.40 SCOP: b.58.1.1 All beta proteins    PK beta-barrel domain-like    PK beta-barrel domain-like    Pyruvate kinase beta-barrel domain    Pyruvate kinase (PK)    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.49.1.1 Alpha and beta proteins (a/b)    Pyruvate kinase C-terminal domain-like    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Escherichia coli GO:  pyruvate kinase activity    pyruvate kinase activity    transferase activity, transferring phosphorus-containing groups    transferase activity, transferring phosphorus-containing groups    glycolysis    glycolysis    CHAIN: B SWISS-PROT/TREMBL: P14178    KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Glycolysis    Kinase    Magnesium    Multigene family    Transferase    EC: 2.7.1.40 SCOP: b.58.1.1 All beta proteins    PK beta-barrel domain-like    PK beta-barrel domain-like    Pyruvate kinase beta-barrel domain    Pyruvate kinase (PK)    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.49.1.1 Alpha and beta proteins (a/b)    Pyruvate kinase C-terminal domain-like    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Escherichia coli GO:  pyruvate kinase activity    pyruvate kinase activity    transferase activity, transferring phosphorus-containing groups    transferase activity, transferring phosphorus-containing groups    glycolysis    glycolysis    CHAIN: C SWISS-PROT/TREMBL: P14178    KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Glycolysis    Kinase    Magnesium    Multigene family    Transferase    EC: 2.7.1.40 SCOP: b.58.1.1 All beta proteins    PK beta-barrel domain-like    PK beta-barrel domain-like    Pyruvate kinase beta-barrel domain    Pyruvate kinase (PK)    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.49.1.1 Alpha and beta proteins (a/b)    Pyruvate kinase C-terminal domain-like    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Escherichia coli GO:  pyruvate kinase activity    pyruvate kinase activity    transferase activity, transferring phosphorus-containing groups    transferase activity, transferring phosphorus-containing groups    glycolysis    glycolysis    CHAIN: D SWISS-PROT/TREMBL: P14178    KEYWORD: 3D-structure    Allosteric enzyme    Complete proteome    Glycolysis    Kinase    Magnesium    Multigene family    Transferase    EC: 2.7.1.40 SCOP: b.58.1.1 All beta proteins    PK beta-barrel domain-like    PK beta-barrel domain-like    Pyruvate kinase beta-barrel domain    Pyruvate kinase (PK)    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.1.12.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Phosphoenolpyruvate/pyruvate domain    Pyruvate kinase    Pyruvate kinase, N-terminal domain    Escherichia coli SCOP: c.49.1.1 Alpha and beta proteins (a/b)    Pyruvate kinase C-terminal domain-like    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Pyruvate kinase, C-terminal domain    Escherichia coli GO:  pyruvate kinase activity    pyruvate kinase activity    transferase activity, transferring phosphorus-containing groups    transferase activity, transferring phosphorus-containing groups    glycolysis    glycolysis

Image Source: PDB

Loops in ArchDB40 clusters

1e0t_A_122 - HA => SUBCLASS : 4.6.1
1e0t_A_396 - EH => SUBCLASS : 2.1.1
1e0t_A_216 - EH => SUBCLASS : 2.4.1
1e0t_A_105 - EH => SUBCLASS : 2.4.8
1e0t_A_374 - EH => SUBCLASS : 3.13.1
1e0t_A_188 - EH => SUBCLASS : 5.8.1
1e0t_A_5 - EH => SUBCLASS : 7.24.1
1e0t_A_141 - AR => SUBCLASS : 1.1.2
1e0t_A_150 - AR => SUBCLASS : 3.1.1
1e0t_A_141 - AR => SUBCLASS : 3.2.8
1e0t_A_83 - AR => SUBCLASS : 4.4.1
1e0t_A_150 - AR => SUBCLASS : 5.13.1
1e0t_A_244 - HH => SUBCLASS : 2.3.1
1e0t_A_244 - HH => SUBCLASS : 2.3.9

Loops in ArchDB95 clusters

1e0t_A_105 - EH => SUBCLASS : 0.1.57
1e0t_A_396 - EH => SUBCLASS : 2.1.1
1e0t_A_216 - EH => SUBCLASS : 2.3.1
1e0t_A_374 - EH => SUBCLASS : 3.18.1
1e0t_A_188 - EH => SUBCLASS : 5.13.1
1e0t_A_5 - EH => SUBCLASS : 6.6.1
1e0t_A_83 - AR => SUBCLASS : 2.3.1
1e0t_A_141 - AR => SUBCLASS : 3.1.1
1e0t_A_141 - AR => SUBCLASS : 3.1.2
1e0t_A_150 - AR => SUBCLASS : 4.2.1
1e0t_A_244 - HH => SUBCLASS : 2.3.3
1e0t_A_244 - HH => SUBCLASS : 2.3.9
1e0t_A_122 - HA => SUBCLASS : 4.6.1

Loops in ArchDB-EC clusters

1e0t_A_244 - HH => SUBCLASS : 2.3.5

Loops in ArchDB-KI clusters

1e0t_A_141 - AR => SUBCLASS : 3.1.1
1e0t_A_253 - HE => SUBCLASS : 1.1.2
1e0t_A_253 - HE => SUBCLASS : 2.1.2
1e0t_A_292 - HE => SUBCLASS : 3.1.2
1e0t_A_172 - HE => SUBCLASS : 3.1.2
1e0t_A_355 - HE => SUBCLASS : 3.1.6
1e0t_A_292 - HE => SUBCLASS : 3.2.1
1e0t_A_172 - HE => SUBCLASS : 3.2.1

Loops not clustered in ArchDB

1e0t_A_62 - AR
1e0t_A_72 - AR
1e0t_A_62 - AR
1e0t_A_72 - AR
1e0t_A_83 - AR
1e0t_A_150 - AR
1e0t_A_141 - AR
1e0t_A_28 - EH
1e0t_A_239 - EH
1e0t_A_415 - EH
1e0t_A_157 - EH
1e0t_A_308 - EH
1e0t_A_273 - EH
1e0t_A_90 - HA
1e0t_A_130 - HA
1e0t_A_448 - HA
1e0t_A_130 - HA
1e0t_A_90 - HA
1e0t_A_122 - HA
1e0t_A_448 - HA
1e0t_A_426 - HE
1e0t_A_17 - HE
1e0t_A_40 - HE
1e0t_A_113 - HE
1e0t_A_172 - HE
1e0t_A_197 - HE
1e0t_A_230 - HE
1e0t_A_253 - HE
1e0t_A_292 - HE
1e0t_A_355 - HE
1e0t_A_382 - HE
1e0t_A_403 - HE
1e0t_A_224 - HH
1e0t_A_322 - HH

Loops not clustered in ArchDB-KI

1e0t_A_62 - AR
1e0t_A_150 - AR
1e0t_A_83 - AR
1e0t_A_72 - AR
1e0t_A_216 - EH
1e0t_A_308 - EH
1e0t_A_273 - EH
1e0t_A_28 - EH
1e0t_A_188 - EH
1e0t_A_105 - EH
1e0t_A_374 - EH
1e0t_A_396 - EH
1e0t_A_239 - EH
1e0t_A_415 - EH
1e0t_A_157 - EH
1e0t_A_5 - EH
1e0t_A_122 - HA
1e0t_A_448 - HA
1e0t_A_130 - HA
1e0t_A_40 - HE
1e0t_A_113 - HE
1e0t_A_197 - HE
1e0t_A_382 - HE
1e0t_A_426 - HE
1e0t_A_403 - HE
1e0t_A_230 - HE
1e0t_A_17 - HE
1e0t_A_224 - HH
1e0t_A_244 - HH
1e0t_A_322 - HH

1e0t A - percentage of sequence identity: 100
1e0t B - percentage of sequence identity: 100
1e0t C - percentage of sequence identity: 100
1e0t D - percentage of sequence identity: 100
1e0u A - percentage of sequence identity: 99
1e0u B - percentage of sequence identity: 99
1e0u C - percentage of sequence identity: 99
1e0u D - percentage of sequence identity: 99
1pky A - percentage of sequence identity: 99
1pky B - percentage of sequence identity: 99
1pky C - percentage of sequence identity: 99
1pky D - percentage of sequence identity: 99