PDB: 1fec Compound: trypanothione reductase Classification: OXIDOREDUCTASE Entry date in PDB: 1997-01-11 Resolution [Å]: 1.70 R-Factor: 0.204

CHAIN: A SWISS-PROT/TREMBL: P39040    KEYWORD: 3D-structure    FAD    Flavoprotein    NADP    Oxidoreductase    Redox-active center    EC: 1.8.1.12 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Trypanothione reductase    Crithidia fasciculata GO:  cytoplasm    disulfide oxidoreductase activity    oxidoreductase activity    electron transport    CHAIN: B SWISS-PROT/TREMBL: P39040    KEYWORD: 3D-structure    FAD    Flavoprotein    NADP    Oxidoreductase    Redox-active center    EC: 1.8.1.12 SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: c.3.1.5 Alpha and beta proteins (a/b)    FAD/NAD(P)-binding domain    FAD/NAD(P)-binding domain    FAD/NAD-linked reductases, N-terminal and central domains    Trypanothione reductase    Crithidia fasciculata SCOP: d.87.1.1 Alpha and beta proteins (a+b)    CO dehydrogenase flavoprotein C-domain-like    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    FAD/NAD-linked reductases, dimerisation (C-terminal) domain    Trypanothione reductase    Crithidia fasciculata GO:  cytoplasm    disulfide oxidoreductase activity    oxidoreductase activity    electron transport

Image Source: PDB

Loops in ArchDB40 clusters

1fec_A_475 - HA => SUBCLASS : 2.1.1
1fec_A_254 - HA => SUBCLASS : 3.1.1
1fec_A_265 - HA => SUBCLASS : 3.1.1
1fec_A_410 - HA => SUBCLASS : 4.1.2
1fec_A_265 - HA => SUBCLASS : 4.2.1
1fec_A_363 - HA => SUBCLASS : 5.24.1
1fec_A_189 - EH => SUBCLASS : 3.2.1
1fec_A_4 - EH => SUBCLASS : 3.2.2
1fec_A_422 - EH => SUBCLASS : 3.20.1
1fec_A_274 - AR => SUBCLASS : 1.1.4
1fec_A_246 - AR => SUBCLASS : 1.2.3
1fec_A_119 - AR => SUBCLASS : 1.3.2
1fec_A_279 - AR => SUBCLASS : 2.6.1
1fec_A_146 - AR => SUBCLASS : 3.11.3
1fec_A_279 - AR => SUBCLASS : 3.12.1
1fec_A_433 - HH => SUBCLASS : 3.2.1

Loops in ArchDB95 clusters

1fec_A_189 - EH => SUBCLASS : 3.5.1
1fec_A_4 - EH => SUBCLASS : 3.5.3
1fec_A_422 - EH => SUBCLASS : 3.11.1
1fec_A_274 - AR => SUBCLASS : 1.2.2
1fec_A_119 - AR => SUBCLASS : 1.3.2
1fec_A_246 - AR => SUBCLASS : 2.6.1
1fec_A_146 - AR => SUBCLASS : 3.15.3
1fec_A_433 - HH => SUBCLASS : 3.1.3
1fec_A_433 - HH => SUBCLASS : 3.2.1
1fec_A_231 - HE => SUBCLASS : 1.2.1
1fec_A_13 - HE => SUBCLASS : 2.1.1
1fec_A_378 - HE => SUBCLASS : 2.3.10
1fec_A_91 - HE => SUBCLASS : 3.7.1
1fec_A_177 - HE => SUBCLASS : 6.10.1
1fec_A_398 - HE => SUBCLASS : 6.56.1
1fec_A_475 - HA => SUBCLASS : 2.1.1
1fec_A_254 - HA => SUBCLASS : 3.1.1
1fec_A_265 - HA => SUBCLASS : 3.1.2
1fec_A_410 - HA => SUBCLASS : 4.1.2
1fec_A_363 - HA => SUBCLASS : 5.16.1

Loops in ArchDB-EC clusters

1fec_A_433 - HH => SUBCLASS : 3.3.1

Loops not clustered in ArchDB

1fec_A_286 - AR
1fec_A_286 - AR
1fec_A_279 - AR
1fec_A_274 - AR
1fec_A_246 - AR
1fec_A_146 - AR
1fec_A_119 - AR
1fec_A_30 - EH
1fec_A_387 - EH
1fec_A_161 - EH
1fec_A_215 - EH
1fec_A_321 - EH
1fec_A_371 - EH
1fec_A_410 - HA
1fec_A_363 - HA
1fec_A_265 - HA
1fec_A_254 - HA
1fec_A_475 - HA
1fec_A_133 - HA
1fec_A_125 - HA
1fec_A_133 - HA
1fec_A_125 - HA
1fec_A_197 - HE
1fec_A_334 - HE
1fec_A_450 - HE
1fec_A_56 - HH
1fec_A_50 - HH

1aog A - percentage of sequence identity: 68
1aog B - percentage of sequence identity: 68
1bzl A - percentage of sequence identity: 68
1bzl B - percentage of sequence identity: 68
1fea A - percentage of sequence identity: 100
1fea B - percentage of sequence identity: 100
1fea C - percentage of sequence identity: 100
1fea D - percentage of sequence identity: 100
1feb A - percentage of sequence identity: 100
1feb B - percentage of sequence identity: 100
1fec A - percentage of sequence identity: 100
1fec B - percentage of sequence identity: 100
1gxf A - percentage of sequence identity: 68
1gxf B - percentage of sequence identity: 68
1nda A - percentage of sequence identity: 69
1nda B - percentage of sequence identity: 69
1nda C - percentage of sequence identity: 69
1nda D - percentage of sequence identity: 69
1typ A - percentage of sequence identity: 99
1typ B - percentage of sequence identity: 99
1tyt A - percentage of sequence identity: 99
1tyt B - percentage of sequence identity: 99
2tpr A - percentage of sequence identity: 99
2tpr B - percentage of sequence identity: 99