PDB: 1fpr Compound: protein-tyrosine phosphatase 1c Classification: SIGNALING PROTEIN Entry date in PDB: 2001-03-07 Resolution [Å]: 2.50 R-Factor: 0.194

CHAIN: A SWISS-PROT/TREMBL: P29350    KEYWORD: 3D-structure    Alternative splicing    Hydrolase    Phosphorylation    Protein phosphatase    Repeat    SH2 domain    EC: 3.1.3.48 SCOP: c.45.1.2 Alpha and beta proteins (a/b)    (Phosphotyrosine protein) phosphatases II    (Phosphotyrosine protein) phosphatases II    Higher-molecular-weight phosphotyrosine protein phosphatases    Tyrosine phosphatase    Human (Homo sapiens), shp-1 GO:  phosphoprotein phosphatase activity    protein tyrosine phosphatase activity    intracellular signaling cascade    protein amino acid dephosphorylation

Image Source: PDB

Loops in ArchDB95 clusters

1fpr_A_486 - HH => SUBCLASS : 7.3.1
1fpr_A_334 - HE => SUBCLASS : 3.1.1
1fpr_A_429 - HE => SUBCLASS : 6.12.1
1fpr_A_429 - HE => SUBCLASS : 6.12.2
1fpr_A_372 - HA => SUBCLASS : 2.3.1
1fpr_A_395 - HA => SUBCLASS : 7.17.1

Loops in ArchDB-EC clusters

1fpr_A_486 - HH => SUBCLASS : 7.4.1

Loops not clustered in ArchDB

1fpr_A_348 - AR
1fpr_A_348 - AR
1fpr_A_322 - EH
1fpr_A_409 - EH
1fpr_A_451 - EH
1fpr_A_395 - HA
1fpr_A_379 - HA
1fpr_A_372 - HA
1fpr_A_309 - HA
1fpr_A_303 - HA
1fpr_A_288 - HA
1fpr_A_379 - HA
1fpr_A_309 - HA
1fpr_A_303 - HA
1fpr_A_288 - HA
1fpr_A_246 - HE
1fpr_A_460 - HH

1gwz - - percentage of sequence identity: 99
2b3o A - percentage of sequence identity: 99
2shp B - percentage of sequence identity: 60