PDB: 1fvr Compound: tyrosine-protein kinase tie-2 Classification: TRANSFERASE Entry date in PDB: 2001-09-20 Resolution [Å]: 2.20 R-Factor: 0.225

CHAIN: A SWISS-PROT/TREMBL: Q02763    KEYWORD: 3D-structure    ATP-binding    Disease mutation    EGF-like domain    Glycoprotein    Immunoglobulin domain    Multigene family    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Tie2 kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation    CHAIN: B SWISS-PROT/TREMBL: Q02763    KEYWORD: 3D-structure    ATP-binding    Disease mutation    EGF-like domain    Glycoprotein    Immunoglobulin domain    Multigene family    Phosphorylation    Receptor    Repeat    Signal    Transferase    Transmembrane    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    Tie2 kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB95 clusters

1fvr_A_1014 - EH => SUBCLASS : 1.1.5
1fvr_A_897 - EH => SUBCLASS : 7.13.1
1fvr_A_978 - AR => SUBCLASS : 5.71.1
1fvr_A_960 - AR => SUBCLASS : 8.5.1
1fvr_A_1065 - HH => SUBCLASS : 9.1.3
1fvr_A_1017 - HH => SUBCLASS : 10.1.1
1fvr_A_1044 - HH => SUBCLASS : 11.4.1
1fvr_A_938 - HE => SUBCLASS : 1.2.1
1fvr_A_1007 - HE => SUBCLASS : 1.2.5
1fvr_A_1007 - HE => SUBCLASS : 1.2.6
1fvr_A_888 - HA => SUBCLASS : 2.1.1
1fvr_A_970 - HA => SUBCLASS : 3.2.1
1fvr_A_825 - HA => SUBCLASS : 3.5.2

Loops in ArchDB-EC clusters

1fvr_A_1017 - HH => SUBCLASS : 10.1.1

Loops in ArchDB-KI clusters

1fvr_B_978 - AR => SUBCLASS : 5.2.1
1fvr_B_960 - AR => SUBCLASS : 8.1.1
1fvr_B_1014 - EH => SUBCLASS : 1.1.5
1fvr_B_888 - HA => SUBCLASS : 2.1.1
1fvr_B_970 - HA => SUBCLASS : 5.4.1
1fvr_B_1007 - HE => SUBCLASS : 1.1.2
1fvr_B_868 - HE => SUBCLASS : 8.2.1

Loops not clustered in ArchDB

1fvr_A_986 - AR
1fvr_A_978 - AR
1fvr_A_960 - AR
1fvr_A_986 - AR
1fvr_A_848 - EH
1fvr_A_991 - EH
1fvr_A_970 - HA
1fvr_A_888 - HA
1fvr_A_837 - HA
1fvr_A_825 - HA
1fvr_A_837 - HA
1fvr_A_868 - HE
1fvr_A_910 - HH
1fvr_A_924 - HH
1fvr_A_919 - HH

Loops not clustered in ArchDB-KI

1fvr_B_986 - AR
1fvr_B_848 - EH
1fvr_B_991 - EH
1fvr_B_897 - EH
1fvr_B_825 - HA
1fvr_B_837 - HA
1fvr_B_938 - HE
1fvr_B_910 - HH
1fvr_B_919 - HH
1fvr_B_1065 - HH
1fvr_B_924 - HH
1fvr_B_1017 - HH
1fvr_B_1044 - HH

1fvr A - percentage of sequence identity: 100
1fvr B - percentage of sequence identity: 100